Qua Kelli, Pelfrey Clara M
School of Medicine, Clinical and Translational Science Collaborative, Case Western Reserve University, Cleveland, OH, USA.
J Clin Transl Sci. 2020 Jul 24;5(1):e24. doi: 10.1017/cts.2020.516.
Evaluating clinical and translational research (CTR) mentored training programs is challenging because no two programs are alike. Careful selection of appropriate metrics is required to make valid comparisons between individuals and between programs. The KL2 program provides mentored-training for early-stage CTR investigators. Clinical and Translational Awards across the country have unique KL2 programs. The evaluation of KL2 programs has begun to incorporate bibliometrics to measure KL2 scholar and program impact.
This study investigated demographic differences in bibliometric performance and post-K award funding of KL2 scholars and compared the bibliometric performance and post-K award federal funding of KL2 scholars and other mentored-K awardees at the same institution. Data for this study included SciVal and iCite bibliometrics and National Institutions of Health RePORTER grant information for mentored-K awardees (K08, K23, and KL2) at Case Western Reserve University between 2005 and 2013.
Results showed no demographics differences within the KL2 program scholars. Bibliometric differences between KL2 and other mentored-K awardee indicated an initial KL2 advantage for the number of publications at 5 years' post-matriculation (i.e., the start of the K award). Regression analyses indicated the number of initial publications was a significant predictor of federal grant funding at the same time point. Analysis beyond the 5-year post-matriculation point did not result in a sustained, significant KL2 advantage.
Factors that contributed to the grant funding advantage need to be determined. Additionally, differences between translational and clinical bibliometrics must be interpreted with caution, and appropriate metrics for translational science must be established.
评估临床与转化研究(CTR)指导培训项目具有挑战性,因为没有两个项目是完全相同的。需要仔细选择合适的指标,以便在个人之间以及项目之间进行有效的比较。KL2项目为早期CTR研究人员提供指导培训。全国各地的临床与转化奖都有独特的KL2项目。对KL2项目的评估已开始纳入文献计量学,以衡量KL2学者和项目的影响力。
本研究调查了KL2学者在文献计量学表现和K奖后资助方面的人口统计学差异,并比较了同一机构中KL2学者与其他接受指导的K奖获得者的文献计量学表现和K奖后联邦资助情况。本研究的数据包括2005年至2013年凯斯西储大学接受指导的K奖获得者(K08、K23和KL2)的SciVal和iCite文献计量学数据以及美国国立卫生研究院RePORTER资助信息。
结果显示KL2项目学者内部不存在人口统计学差异。KL2与其他接受指导的K奖获得者之间的文献计量学差异表明,在入学后5年(即K奖开始时),KL2在出版物数量方面具有初步优势。回归分析表明,初始出版物数量是同一时间点联邦资助的一个重要预测指标。入学后5年之后的分析并未产生持续、显著的KL2优势。
需要确定促成资助优势的因素。此外,必须谨慎解释转化文献计量学和临床文献计量学之间的差异,并建立适用于转化科学的合适指标。