Genedi Ahmed Magdi Mohamed, Elzayat Ahmed Mohamed, Mohamed Mohamed Mohsen, Elmenshawy Mahmoud Diaa
Resident of Cardiology, Shark Elmadina Hospital, Alexandria, Egypt.
Faculty of Medicine, Zagazig University, Egypt.
Heliyon. 2021 Apr 17;7(4):e06807. doi: 10.1016/j.heliyon.2021.e06807. eCollection 2021 Apr.
Hospital length of stay (LOS) is a key determinant of heart failure hospitalization costs and performance of medical care quality. Right ventricular (RV) dysfunction predicted poor outcome in patients with acute heart failure (AHF).
To study the effect of right ventricular function on length of hospital stay as a predictor in patients with acute heart failure.
A prospective cohort study was conducted in Cardiology Care Units (CCUs) in Zagazig University Hospital and Shark El Madina Hospital from September 2019 to February 2020, we included in this study 99 patients admitted with AHF. Clinical data and baseline RV function assessed by tricuspid annular plane systolic excursion (TAPSE) and S' velocity were collected. Clinical comorbidities including worsening renal function (WRF) were monitored during hospitalization. The primary outcome was hospital LOS.
There was statistically significant correlation between WRF, right ventricular systolic dysfunction identified by TAPSE<16 mm and S' <9.5 cm/s and poor outcome in patients with acute heart failure including prolonged LOS.
Right ventricular (RV) systolic dysfunction as assessed by TAPSE and S' velocity and diastolic dysfunction were independent predictors of longer LOS in AHF patients. WRF had high prevalence among patients with AHF and associated with poor outcome in AHF patients and prolonged LOS.
住院时间是心力衰竭住院费用和医疗质量表现的关键决定因素。右心室功能障碍预示着急性心力衰竭(AHF)患者的不良预后。
研究右心室功能对急性心力衰竭患者住院时间的影响,作为一种预测指标。
2019年9月至2020年2月在扎加济格大学医院和鲨鱼城麦地那医院的心脏病监护病房(CCU)进行了一项前瞻性队列研究,本研究纳入了99例因AHF入院的患者。收集临床数据以及通过三尖瓣环平面收缩期位移(TAPSE)和S'速度评估的基线右心室功能。住院期间监测包括肾功能恶化(WRF)在内的临床合并症。主要结局是住院时间。
在急性心力衰竭患者中,WRF、通过TAPSE<16 mm和S'<9.5 cm/s确定的右心室收缩功能障碍与不良预后(包括住院时间延长)之间存在统计学显著相关性。
通过TAPSE和S'速度评估的右心室(RV)收缩功能障碍和舒张功能障碍是AHF患者住院时间延长的独立预测因素。WRF在AHF患者中患病率很高,并且与AHF患者的不良预后和住院时间延长相关。