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专科特定再入院风险模型在估计肝胰胆外科再入院风险方面优于通用模型。

Specialty-Specific Readmission Risk Models Outperform General Models in Estimating Hepatopancreatobiliary Surgery Readmission Risk.

机构信息

Department of Surgery, University of Virginia, Box 800709, Charlottesville, VA, 22908-0709, USA.

Surgical Outcomes Research Center, University of Virginia, Charlottesville, VA, USA.

出版信息

J Gastrointest Surg. 2021 Dec;25(12):3074-3083. doi: 10.1007/s11605-021-05023-z. Epub 2021 May 4.

Abstract

BACKGROUND

Readmissions are costly and inconvenient for patients, and occur frequently in hepatopancreatobiliary (HPB) surgery practice. Readmission prediction tools exist, but most have not been designed or tested in the HPB patient population.

METHODS

Pancreatectomy and hepatectomy operation-specific readmission models defined as subspecialty readmission risk assessments (SRRA) were developed using clinically relevant data from merged 2014-15 ACS NSQIP Participant Use Data Files and Procedure Targeted datasets. The two derived procedure-specific models were tested along with 6 other readmission models in institutional validation cohorts in patients who had pancreatectomy or hepatectomy, respectively, between 2013 and 2017. Models were compared using area under the receiver operating characteristic curves (AUC).

RESULTS

A total of 16,884 patients (9169 pancreatectomy and 7715 hepatectomy) were included in the derivation models. A total of 665 patients (383 pancreatectomy and 282 hepatectomy) were included in the validation models. Specialty-specific readmission models outperformed general models. AUC characteristics of the derived pancreatectomy and hepatectomy SRRA (pancreatectomy AUC=0.66, hepatectomy AUC=0.74), modified Readmission After Pancreatectomy (AUC=0.76), and modified Readmission Risk Score for hepatectomy (AUC=0.78) outperformed general models for readmission risk: LOS/2 + ASA integer-based score (pancreatectomy AUC=0.58, hepatectomy AUC=0.66), LACE Index (pancreatectomy AUC=0.54, hepatectomy AUC=0.62), Unplanned Readmission Nomogram (pancreatectomy AUC=0.52, hepatectomy AUC=0.55), and institutional ARIA (pancreatectomy AUC=0.46, hepatectomy AUC=0.58).

CONCLUSION

HPB readmission risk models using 30-day subspecialty-specific data outperform general readmission risk tools. Hospitals and practices aiming to decrease readmissions in HPB surgery patient populations should use specialty-specific readmission reduction strategies.

摘要

背景

再入院对患者来说既昂贵又不便,并且在肝胆胰外科(HPB)手术实践中经常发生。虽然存在再入院预测工具,但大多数工具都不是针对 HPB 患者人群设计或测试的。

方法

使用合并的 2014-15 年 ACS NSQIP 参与者使用数据文件和针对特定程序的数据集的临床相关数据,定义了胰腺切除术和肝切除术特定于操作的再入院模型,这些模型被定义为专科再入院风险评估(SRRA)。在分别于 2013 年至 2017 年期间接受胰腺切除术或肝切除术的患者的机构验证队列中,测试了这两个衍生的特定于程序的模型以及其他 6 个再入院模型。使用接收者操作特征曲线下的面积(AUC)比较模型。

结果

共有 16884 名患者(9169 名胰腺切除术和 7715 名肝切除术)纳入了推导模型。共有 665 名患者(383 名胰腺切除术和 282 名肝切除术)纳入了验证模型。专科特定的再入院模型优于通用模型。推导的胰腺切除术和肝切除术 SRRA 的 AUC 特征(胰腺切除术 AUC=0.66,肝切除术 AUC=0.74)、改良的胰腺切除术后再入院(AUC=0.76)和改良的肝切除术再入院风险评分(AUC=0.78)优于通用模型的再入院风险:LOS/2+ASA 整数评分(胰腺切除术 AUC=0.58,肝切除术 AUC=0.66)、LACE 指数(胰腺切除术 AUC=0.54,肝切除术 AUC=0.62)、计划外再入院预测图(胰腺切除术 AUC=0.52,肝切除术 AUC=0.55)和机构 ARIA(胰腺切除术 AUC=0.46,肝切除术 AUC=0.58)。

结论

使用 30 天专科特定数据的 HPB 再入院风险模型优于通用再入院风险工具。旨在降低 HPB 手术患者人群再入院率的医院和实践应使用专科特定的再入院减少策略。

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