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择期肝切除术后非计划性再入院的可能可预防原因,来自一家非学术性转诊肝胆中心的结果。

Possible Preventable Causes of Unplanned Readmission After Elective Liver Resection, Results from a Non-academic Referral HPB Center.

机构信息

Department of Surgery, Medisch Spectrum Twente, Enschede, The Netherlands.

Department of Research and Innovation, Isala, Zwolle, The Netherlands.

出版信息

World J Surg. 2019 Jul;43(7):1802-1808. doi: 10.1007/s00268-019-04970-8.

Abstract

INTRODUCTION

Unplanned readmission is a common event after liver resection, and it is a burden for both patients and healthcare policy makers. This study evaluates the incidence of and reasons for unplanned readmission after liver resection, in order to identify possible preventable causes.

METHODS

In this single-center cohort study, data from patients who underwent liver resection for both malignant and benign indications from 2001 to 2016 at our institute were collected from a database with prospective data. Readmissions were analyzed for their reasons and risk factors. Patients with general complaints with no specific complications were categorized as failure to thrive.

RESULTS

In 406 patients, the readmission rate was 11.6%. Most patients were readmitted because of failure to thrive (35%), deep and superficial surgical site infection (28%), or cardiopulmonary complications (15%). A multivariate analysis revealed that unplanned readmission was associated with the occurrence of complications during index admission-with an odds ratio of 4.69 (CI 2.41-9.12, p < 0.001).

CONCLUSION

Readmission occurs in more than 1 in 10 patients after liver resection, and it is associated with a complicated course during index admission. One-third of readmissions occur because of failure to thrive and might be preventable. Future research in strategies to reduce readmission rates should focus on both the prevention of complications during index admission and programs at the interface between primary and secondary care.

摘要

引言

肝切除术后的非计划性再入院是一种常见事件,这对患者和医疗保健政策制定者来说都是一种负担。本研究评估了肝切除术后非计划性再入院的发生率和原因,以确定可能的可预防原因。

方法

在这项单中心队列研究中,我们从 2001 年至 2016 年在我们医院因良恶性疾病行肝切除术的患者数据库中收集了前瞻性数据,分析了再入院的原因和危险因素。因一般不适而无特定并发症的患者被归类为生长不良。

结果

在 406 例患者中,再入院率为 11.6%。大多数患者因生长不良(35%)、深部和浅部手术部位感染(28%)或心肺并发症(15%)而再次入院。多变量分析显示,非计划性再入院与指数入院期间并发症的发生有关,比值比为 4.69(95%CI 2.41-9.12,p<0.001)。

结论

肝切除术后超过 1/10 的患者会发生再入院,且与指数入院期间的复杂病程有关。三分之一的再入院是由于生长不良引起的,这可能是可以预防的。未来减少再入院率的研究应集中在预防指数入院期间的并发症和初级保健与二级保健之间的衔接计划上。

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