Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati College of Medicine, 231 Albert B. Sabin Way ML 0542, Cincinnati, OH, USA.
Division of Biostatistics and Epidemiology, Department of Molecular and Translational Medicine, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
J Nucl Cardiol. 2022 Aug;29(4):1976-1984. doi: 10.1007/s12350-021-02632-8. Epub 2021 May 4.
Breast attenuation artifacts occurring with upright cadmium-zinc-telluride (CZT) cardiac imaging systems have not been well characterized.
216 consecutive patients with Single Photon Emission Computerized Tomography myocardial perfusion imaging and no angiographically significant obstructive coronary artery disease were identified. All upright and supine SPECT images as well as coronary angiograms were reviewed and analyzed in blinded fashion.
In women imaged upright, more visual false positive defects were noted in the inferior wall compared to the anterior wall (26 vs. 10 at rest, p = 0.006, and 33 vs. 13 at stress, p < 0.001). Visual inferior wall defects were more common in the upright than supine position at stress (33 vs. 23, p = 0.018) and rest (26 vs. 14, p = 0.011), and most apparent in non-obese women (13 vs. 8, at stress, p = 0.059 and 11 vs. 5, at rest, p = 0.014).
With upright CZT myocardial perfusion imaging, women often have visible inferior wall attenuation artifact defects, likely from pendant breast tissue. These inferior wall attenuation artifacts may be seen in non-obese female patients.
直立式碲锌镉（CZT）心脏成像系统中出现的乳腺衰减伪影尚未得到很好的描述。
确定了 216 例连续接受单光子发射计算机断层心肌灌注成像且无明显冠状动脉阻塞性疾病的患者。所有直立和仰卧位 SPECT 图像以及冠状动脉造影均以盲法进行回顾性分析。
在直立位成像的女性中，与前壁相比，下壁更易出现视觉上的假阳性缺陷（静息时分别为 26 处和 10 处，p=0.006，应激时分别为 33 处和 13 处，p<0.001）。应激时下壁缺陷在直立位比仰卧位更常见（33 处比 23 处，p=0.018）和静息时（26 处比 14 处，p=0.011），在非肥胖女性中最为明显（应激时分别为 13 处和 8 处，p=0.059，静息时分别为 11 处和 5 处，p=0.014）。
在直立式 CZT 心肌灌注成像中，女性常出现可见的下壁衰减伪影缺陷，可能是由于悬垂的乳腺组织所致。这些下壁衰减伪影可能见于非肥胖的女性患者。
