慢性阻塞性肺疾病患者在哥伦比亚加勒比地区的生活质量和抑郁情况。

Quality of life and depression in COPD patients in the Colombian Caribbean.

机构信息

Facultad de Ciencias de la Salud, Universidad del Magdalena, Santa Marta, Colombia.

出版信息

Clin Respir J. 2021 Sep;15(9):944-948. doi: 10.1111/crj.13385. Epub 2021 May 14.

DOI:10.1111/crj.13385

PMID:33949121

Abstract

OBJECTIVE

To establish the association between quality of life and depression among COPD patients of the Colombian Caribbean.

METHOD

A cross-sectional study was carried out with the participation of adult COPD patients. COPD-related quality of life was quantified with the COPD Assessment Test (CAT) and depression using the Zung 10-item Self-rating Depression Scale (SDS-10). The relationship between COPD-related quality of life and depression with odds ratios (OR), crude and adjusted, was determined.

RESULTS

408 patients participated in the study. They were aged between 40 and 102 years (mean = 72.9, SD = 10.2) and 58.8% men. Two hundred eighty-four patients (69.6%) reported worse health status (CAT ≥10), and 114 patients (27.9%) scored for depression (SDS-10). Patients with worse health status presented more depression (OR = 5.85, 95% CI 3.01-11.36) and after adjusting for gender (OR = 5.70, 95% CI 2.92-11.13).

CONCLUSIONS

In patients with COPD and CAT ≥10, there is a five times greater risk of depression than patients with CAT <10. However, the relationship may be bidirectional. It is essential to specify the direction of causality in future investigations.

摘要

目的

建立哥伦比亚加勒比地区 COPD 患者生活质量与抑郁之间的关联。

方法

进行了一项横断面研究，参与者为成年 COPD 患者。使用 COPD 评估测试（CAT）量化与 COPD 相关的生活质量，使用zung10 项自评抑郁量表（SDS-10）评估抑郁。使用比值比（OR）、粗值和调整值确定与 COPD 相关的生活质量和抑郁之间的关系。

结果

408 名患者参与了这项研究。他们的年龄在 40 至 102 岁之间（平均值=72.9，标准差=10.2），58.8%为男性。284 名患者（69.6%）报告健康状况较差（CAT≥10），114 名患者（27.9%）评分抑郁（SDS-10）。健康状况较差的患者更易出现抑郁（OR=5.85，95%CI 3.01-11.36），调整性别后（OR=5.70，95%CI 2.92-11.13），这一关联依然存在。