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超声检查宫颈短的单胎妊娠行宫颈环扎术或保守治疗的母婴结局分析。

Analysis of maternal and neonatal outcomes using cervical cerclage or conservative treatment in singleton gestations with a sonographic short cervix.

机构信息

Department of Obstetrics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China.

出版信息

Medicine (Baltimore). 2021 May 7;100(18):e25767. doi: 10.1097/MD.0000000000025767.

DOI:10.1097/MD.0000000000025767
PMID:33950964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8104303/
Abstract

To investigate the effect of cervical cerclage or conservative treatment on maternal and neonatal outcomes in singleton gestations with a sonographic short cervix, and further compare the relative treatment value.A retrospective study was conducted among women with singleton gestations who had a short cervical length (<25 mm) determined by ultrasound during the period of 14 to 24 weeks' gestation in our institution. We collected clinical data and grouped the patients according to a previous spontaneous preterm birth (PTB) at <34 weeks of gestation or second trimester loss (STL) and sub-grouped according to treatment option, further comparing the maternal and neonatal outcomes between different groups.In the PTB or STL history cohort, the cerclage group had a later gestational age at delivery (35.3 ± 3.9 weeks vs 31.6 ± 6.7 weeks) and a lower rate of perinatal deaths (2% vs 29.3%) compared with the conservative treatment group. In the non-PTB-STL history cohort, the maternal and neonatal outcomes were not significantly different between the cerclage group and conservative treatment group. More importantly, for patients with a sonographic short cervix who received cervical cerclage, there was no significant difference in the maternal and neonatal outcomes between the non-PTB-STL group and PTB or STL group.For singleton pregnant with a history of spontaneous PTB or STL and a short cervical length (<25 mm), cervical cerclage can significantly improve maternal and neonatal outcomes; however, conservative treatment (less invasive and expensive than cervical cerclage) was more suitable for those pregnant women without a previous PTB and STL history.

摘要

探讨经阴道超声测量宫颈短于 25mm 的单胎妊娠行宫颈环扎术或保守治疗对母婴结局的影响,并进一步比较其相对治疗价值。

本研究为回顾性队列研究,纳入在我院行经阴道超声检查发现宫颈长度<25mm 的单胎妊娠孕妇,收集其临床资料,根据是否有自发性早产史(<34 周)或中孕期流产史分组,根据治疗方案进一步分组,比较不同组间母婴结局。

在自发性早产史或中孕期流产史组中,与保守治疗组相比,行宫颈环扎术组的分娩孕周更晚(35.3±3.9 周 vs. 31.6±6.7 周),围产儿病死率更低(2% vs. 29.3%)。在无自发性早产史或中孕期流产史组中,宫颈环扎术组与保守治疗组的母婴结局差异无统计学意义。更重要的是,对于行宫颈环扎术的宫颈短孕妇,无论是否有自发性早产史或中孕期流产史,其母婴结局差异均无统计学意义。

对于有自发性早产史或中孕期流产史且宫颈短(<25mm)的单胎妊娠孕妇,行宫颈环扎术可明显改善母婴结局;但对于无自发性早产史和中孕期流产史的孕妇,行保守治疗(相对于宫颈环扎术创伤更小、花费更少)可能更适合。

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