Biochemical parameters of slowly liquefying human ejaculates.

Abnormality in liquefaction of human semen is associated with poor scoring in postcoital tests and may lead to subfertility. A relative study on the seminal plasma characteristics of slowly and normally liquefying human ejaculates has been made. A multitude of seminal vesicular and prostatic components in the seminal plasma of eight slow-liquefying ejaculates from 4 men were compared with ten normally liquefying ejaculates from different healthy volunteers. For 60% liquefaction, the time taken by these two types of ejaculates was 46 and 7 min, respectively. The levels of the components that are mainly secreted by the seminal vesicles were similar in both the groups. But all the prostatic components demonstrated significantly (p less than 0.001) decreased levels in the slow-liquefying group from those in the group being compared. It was concluded that relative decrease in the prostatic activity with respect to that of the seminal vesicles appears to be the cause of slow-liquefaction.