Department of Radiation Oncology, University of Lübeck, Lübeck, Germany;
Department of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Anticancer Res. 2021 May;41(5):2489-2494. doi: 10.21873/anticanres.15026.
BACKGROUND/AIM: Most patients with breast cancer are assigned to radiotherapy, which may cause fears leading to sleep disorders. Very few data are available regarding the prevalence of sleep disorders and corresponding risk factors.
Data of 175 patients with breast cancer presenting for adjuvant radiotherapy were retrospectively analyzed. Twenty-three patient and tumor characteristics were investigated for associations with pre-radiotherapy sleep disorders.
Seventy-eight patients (44.6%) stated sleep disorders prior to radiotherapy. These were significantly associated with higher distress score (p<0.0001); greater number of emotional (p<0.0001), physical (p<0.0001) or practical problems (p<0.001); and request for psycho-oncological support (p<0.001). Trends were found for worse performance status (p=0.062) and higher comorbidity index (p=0.059).
Sleep disorders prior to radiotherapy for breast cancer are common. This applies particularly to patients with risk factors including distress due to emotional, physical or practical problems. These patients should be offered psycho-oncological support as soon as possible.
背景/目的：大多数乳腺癌患者被分配接受放疗，这可能导致恐惧，导致睡眠障碍。关于睡眠障碍的患病率和相应的危险因素，只有很少的数据。
回顾性分析了 175 名接受辅助放疗的乳腺癌患者的数据。调查了 23 项患者和肿瘤特征与放疗前睡眠障碍的关系。
78 名患者（44.6%）在放疗前报告有睡眠障碍。这些与较高的困扰评分显著相关（p<0.0001）；更多的情绪（p<0.0001）、身体（p<0.0001）或实际问题（p<0.001）；以及对心理肿瘤学支持的需求（p<0.001）。发现表现状态更差（p=0.062）和合并症指数更高（p=0.059）的趋势。
乳腺癌放疗前的睡眠障碍很常见。这尤其适用于存在因情绪、身体或实际问题而导致困扰等危险因素的患者。这些患者应尽快获得心理肿瘤学支持。
