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Inactivation of the GATA Cofactor ZFPM1 Results in Abnormal Development of Dorsal Raphe Serotonergic Neuron Subtypes and Increased Anxiety-Like Behavior.GATA 辅因子 ZFPM1 的失活导致背侧中缝血清素能神经元亚型的异常发育和焦虑样行为增加。
J Neurosci. 2020 Nov 4;40(45):8669-8682. doi: 10.1523/JNEUROSCI.2252-19.2020. Epub 2020 Oct 12.
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Different roles of distinct serotonergic pathways in anxiety-like behavior, antidepressant-like, and anti-impulsive effects.不同 5-羟色胺能通路在焦虑样行为、抗抑郁样和抗冲动作用中的不同作用。
Neuropharmacology. 2020 May 1;167:107703. doi: 10.1016/j.neuropharm.2019.107703. Epub 2019 Jul 9.
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Multinational comparison of new antidepressant use in older adults: a cohort study.多国家比较老年人中新型抗抑郁药的使用情况：一项队列研究。
BMJ Open. 2019 May 14;9(5):e027663. doi: 10.1136/bmjopen-2018-027663.
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Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity.血清素缺乏通过调节海马体活动增强情境依赖性恐惧学习。
Front Neurosci. 2019 Apr 24;13:245. doi: 10.3389/fnins.2019.00245. eCollection 2019.
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A Shift in the Activation of Serotonergic and Non-serotonergic Neurons in the Dorsal Raphe Lateral Wings Subnucleus Underlies the Panicolytic-Like Effect of Fluoxetine in Rats.氟西汀在大鼠中产生的类似惊恐样效应的基础是背侧中缝外侧亚核中 5-羟色胺能和非 5-羟色胺能神经元的激活转变。
Mol Neurobiol. 2019 Sep;56(9):6487-6500. doi: 10.1007/s12035-019-1536-z. Epub 2019 Mar 7.
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Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems.解剖定义和功能不同的中缝背核 5-羟色胺亚系统。
Cell. 2018 Oct 4;175(2):472-487.e20. doi: 10.1016/j.cell.2018.07.043. Epub 2018 Aug 23.
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Differential modulation of CA1 impulse flow by endogenous serotonin along the hippocampal longitudinal axis.内源性血清素沿着海马纵轴对 CA1 冲动流的差异调节。
Hippocampus. 2018 Mar;28(3):217-225. doi: 10.1002/hipo.22825. Epub 2018 Jan 10.
8
Object Phobia and Altered RhoA Signaling in Amygdala of Mice Lacking RICH2.缺乏RICH2的小鼠杏仁核中的物体恐惧症与RhoA信号改变
Front Mol Neurosci. 2017 Jun 8;10:180. doi: 10.3389/fnmol.2017.00180. eCollection 2017.
9
Specific Connectivity and Unique Molecular Identity of MET Receptor Tyrosine Kinase Expressing Serotonergic Neurons in the Caudal Dorsal Raphe Nuclei.尾背侧中缝核中表达MET受体酪氨酸激酶的5-羟色胺能神经元的特定连接性和独特分子特征
ACS Chem Neurosci. 2017 May 17;8(5):1053-1064. doi: 10.1021/acschemneuro.7b00020. Epub 2017 May 1.
10
Epigenome-Wide Association Study of Wellbeing.幸福感的全表观基因组关联研究
Twin Res Hum Genet. 2015 Dec;18(6):710-9. doi: 10.1017/thg.2015.85. Epub 2015 Dec 1.

ZFPM1 Necessary for Development of Serotonergic Projections Related to Anxiety and Contextual Fear Learning.

作者信息

Taira Masakazu, Desforges Miles J

机构信息

Neural Computation Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son 904-0495, Okinawa, Japan

出版信息

J Neurosci. 2021 May 5;41(18):3945-3947. doi: 10.1523/JNEUROSCI.3125-20.2021.

DOI:10.1523/JNEUROSCI.3125-20.2021
PMID:33952623
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8176756/
Abstract
摘要