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丹麦全国性研究:COVID-19 大流行开始后 7 周内非计划性医院就诊和死亡趋势。

Nationwide study on trends in unplanned hospital attendance and deaths during the 7 weeks after the onset of the COVID-19 pandemic in Denmark.

机构信息

Odense Patient Exploratory Network (OPEN), University of Southern Denmark, Odense, Syddanmark, Denmark.

Department of Emergency Medicine, Sydvestjysk Sygehus Esbjerg, Esbjerg, Denmark.

出版信息

BMJ Qual Saf. 2021 Dec;30(12):986-995. doi: 10.1136/bmjqs-2020-012144. Epub 2021 May 5.

Abstract

BACKGROUND

The impact of a pandemic on unplanned hospital attendance has not been extensively examined. The aim of this study is to report the nationwide consequences of the COVID-19 pandemic on unplanned hospital attendances in Denmark for 7 weeks after a 'shelter at home' order was issued.

METHODS

We merged data from national registries (Civil Registration System and Patient Registry) to conduct a study of unplanned (excluding outpatient visits and elective surgery) hospital-based healthcare and mortality of all Danes. Using data for 7 weeks after the 'shelter at home' order, the incidence rate of unplanned hospital attendances per week in 2020 was compared with corresponding weeks in 2017-2019. The main outcome was hospital attendances per week as incidence rate ratios. Secondary outcomes were general population mortality and risk of death in-hospital, reported as weekly mortality rate ratios (MRRs).

RESULTS

From 2 438 286 attendances in the study period, overall unplanned attendances decreased by up to 21%; attendances excluding COVID-19 were reduced by 31%; non-psychiatric by 31% and psychiatric by 30%. Out of the five most common diagnoses expected to remain stable, only schizophrenia and myocardial infarction remained stable, while chronic obstructive pulmonary disease exacerbation, hip fracture and urinary tract infection fell significantly. The nationwide general population MRR rose in six of the recorded weeks, while MRR excluding patients who were COVID-19 positive only increased in two.

CONCLUSION

The COVID-19 pandemic and a governmental national 'shelter at home' order was associated with a marked reduction in unplanned hospital attendances with an increase in MRR for the general population in two of 7 weeks, despite exclusion of patients with COVID-19. The findings should be taken into consideration when planning for public information campaigns.

摘要

背景

大流行对非计划性医院就诊的影响尚未得到广泛研究。本研究旨在报告 COVID-19 大流行对丹麦发布“居家避难”令后 7 周内非计划性医院就诊的全国性影响。

方法

我们合并了来自国家登记处(公民登记系统和患者登记处)的数据,对所有丹麦人的非计划性(不包括门诊就诊和择期手术)基于医院的医疗保健和死亡率进行了研究。使用“居家避难”令发布后 7 周的数据,将 2020 年每周非计划性医院就诊的发病率与 2017-2019 年同期的相应周进行比较。主要结局是每周就诊人次的发病率比。次要结局是一般人群死亡率和院内死亡风险,以每周死亡率比(MRR)报告。

结果

在研究期间的 2438286 人次就诊中,总体非计划性就诊减少了 21%;不包括 COVID-19 的就诊减少了 31%;非精神科就诊减少了 31%,精神科就诊减少了 30%。在预计保持稳定的五个最常见诊断中,只有精神分裂症和心肌梗死保持稳定,而慢性阻塞性肺疾病加重、髋部骨折和尿路感染则显著下降。全国范围内,在记录的六个星期中,一般人群的 MRR 上升,而仅排除 COVID-19 阳性患者的 MRR 仅在两个星期内上升。

结论

COVID-19 大流行和政府的全国性“居家避难”令与非计划性医院就诊显著减少相关,尽管排除了 COVID-19 患者,但在 7 个星期中的两个星期内,一般人群的 MRR 增加。在规划公共信息宣传活动时应考虑到这些发现。

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