Bowman L K, Cranney G B, Hopkins A P, Wicks J, Walsh W F
Department of Cardiovascular Medicine, Prince Henry Hospital, NSW, Little Bay.
Aust N Z J Med. 1988 Feb;18(1):53-60. doi: 10.1111/j.1445-5994.1988.tb02241.x.
The noninvasive measurement of aortic valve area by use of the continuity equation has been proposed as an accurate method for determining the severity of aortic stenosis. In 32 patients (mean age 64 +/- 14 years) with proven aortic stenosis and without significant regurgitation, aortic valve areas derived by the Gorlin equation from cardiac catheterisation data were compared with valve areas calculated from the continuity equation using Doppler echocardiography. There was a close correlation between Doppler and catheter derived aortic valve areas (r = 0.87, SEE = 0.17 cm2). The interobserver error for aortic valve area measurement in 20 patients was 9.0 +/- 6.8%. The specificity of this method for critical aortic stenosis (aortic valve area less than 0.75 cm2) was 73% and the sensitivity 88%. We conclude that in an adult, predominantly elderly population with calcific aortic stenosis, this Doppler echocardiographic method is reproducible and can be used accurately to derive aortic valve area.
利用连续性方程对主动脉瓣面积进行无创测量,已被提议作为确定主动脉瓣狭窄严重程度的一种准确方法。在32例已证实患有主动脉瓣狭窄且无明显反流的患者(平均年龄64±14岁)中,将通过戈林方程从心导管检查数据得出的主动脉瓣面积与使用多普勒超声心动图根据连续性方程计算出的瓣膜面积进行比较。多普勒测量值与心导管测量值得出的主动脉瓣面积之间存在密切相关性(r = 0.87,标准误 = 0.17 cm²)。20例患者中主动脉瓣面积测量的观察者间误差为9.0±6.8%。该方法对重度主动脉瓣狭窄(主动脉瓣面积小于0.75 cm²)的特异性为73%,敏感性为88%。我们得出结论,在以钙化性主动脉瓣狭窄为主的成年人群(主要为老年人)中,这种多普勒超声心动图方法具有可重复性,可准确用于得出主动脉瓣面积。