Department of Internal Medicine and Paediatrics, Ghent University Hospital, Ghent, Belgium.
European Kidney Health Alliance (EKHA), Brussels, Belgium.
Nat Rev Nephrol. 2021 Aug;17(8):554-568. doi: 10.1038/s41581-021-00425-3. Epub 2021 May 5.
Although overall donation and transplantation activity is higher in Europe than on other continents, differences between European countries in almost every aspect of transplantation activity (for example, in the number of transplantations, the number of people with a functioning graft, in rates of living versus deceased donation, and in the use of expanded criteria donors) suggest that there is ample room for improvement. Herein we review the policy and clinical measures that should be considered to increase access to transplantation and improve post-transplantation outcomes. This Roadmap, generated by a group of major European stakeholders collaborating within a Thematic Network, presents an outline of the challenges to increasing transplantation rates and proposes 12 key areas along with specific measures that should be considered to promote transplantation. This framework can be adopted by countries and institutions that are interested in advancing transplantation, both within and outside the European Union. Within this framework, a priority ranking of initiatives is suggested that could serve as the basis for a new European Union Action Plan on Organ Donation and Transplantation.
尽管欧洲的整体捐赠和移植活动高于其他各大洲,但欧洲各国在移植活动的几乎各个方面(例如,移植数量、有功能移植物的人数、活体与死体捐赠率以及扩展标准供者的使用)都存在差异,这表明仍有很大的改进空间。本文中,我们综述了应考虑采取的政策和临床措施,以增加移植机会并改善移植后的结果。该路线图由一个主要的欧洲利益相关者小组在一个专题网络内合作制定,概述了提高移植率所面临的挑战,并提出了 12 个关键领域以及应考虑采取的具体措施,以促进移植。有兴趣在欧盟内外推进移植的国家和机构均可采用该框架。在此框架内,建议对各项举措进行优先级排序,为制定新的欧盟器官捐赠与移植行动计划提供依据。