巨细胞性心肌炎
Giant cell myocarditis.
作者信息
Gadela Naga Vaishnavi, Krishnan Anand Muthu, Mukarram Osama, Sthalekar Nitya
机构信息
Department of Internal Medicine, University of Connecticut, Farmington, Connecticut.
Department of Cardiology, University of Vermont, Burlington, Vermont.
出版信息
Proc (Bayl Univ Med Cent). 2021 Jan 22;34(3):401-402. doi: 10.1080/08998280.2021.1874775.
Giant cell myocarditis (GCM) usually affects previously healthy adults and is a rapidly progressive and frequently fatal disease. It has a median survival of 3 months to death or transplant without appropriate therapy. Hence, early diagnosis is critical, with evidence showing rapidly instituted cyclosporine-based immunosuppression can improve transplant-free survival. Although transplant is an effective strategy, GCM can recur in 25% of transplanted hearts. We present a case of GCM in a patient who presented with conduction abnormalities and fulminant heart failure.
巨细胞性心肌炎（GCM）通常影响既往健康的成年人，是一种进展迅速且常致命的疾病。若无适当治疗，其从发病到死亡或移植的中位生存期为3个月。因此，早期诊断至关重要，有证据表明迅速开始基于环孢素的免疫抑制治疗可提高无移植生存期。尽管心脏移植是一种有效的治疗策略，但25%的移植心脏会复发GCM。我们报告一例表现为传导异常和暴发性心力衰竭的GCM患者。
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