Basher Fahmin, Camargo Jose F, Diaz-Paez Meilin, Lekakis Lazaros J, Pereira Denise L
Division of General Internal Medicine, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Clin Med Insights Case Rep. 2021 Apr 19;14:11795476211009811. doi: 10.1177/11795476211009811. eCollection 2021.
SARS-CoV-2 emerged as a worldwide pandemic in late 2019 and initially was described as a primary respiratory illness. The clinical manifestations of COVID-19 are now known to encompass nearly all organ systems, including the central nervous system. We present a case of an allogeneic hematopoietic stem cell transplant recipient who recovered from documented SARS-CoV-2 infection and later presented with symptoms of meningitis. While cerebrospinal fluid analysis did not reveal any bacterial or viral etiologies, evidence of an inflammatory state, including ophthalmologic findings of episcleritis, indicate what is likely the first reported case of aseptic meningitis associated with SARS-CoV-2 infection after initial clinical recovery.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）于2019年末演变成一场全球大流行疾病，最初被描述为一种主要的呼吸道疾病。如今已知2019冠状病毒病（COVID-19）的临床表现几乎涵盖所有器官系统，包括中枢神经系统。我们报告一例异基因造血干细胞移植受者，该患者从确诊的SARS-CoV-2感染中康复，后来出现脑膜炎症状。虽然脑脊液分析未发现任何细菌或病毒病因，但包括巩膜炎眼科检查结果在内的炎症状态证据表明，这可能是首例报告的在初始临床康复后与SARS-CoV-2感染相关的无菌性脑膜炎病例。
