Ford D K, Reid G D, Magge S, Schumacher H R
Department of Medicine, University of British Columbia, Vancouver, Canada.
Arthritis Rheum. 1988 Jul;31(7):914-7. doi: 10.1002/art.1780310714.
A 48-year-old man with "rheumatoid arthritis" of 3 years duration was found to have synovial fluid lymphocytes that were maximally stimulated in vitro by chlamydial antigen, on 5 of 6 tests over 18 months. Immunocytochemical staining of a synovectomy specimen, using the peroxidase-antiperoxidase technique, subsequently revealed chlamydial antigen in the synovium. The possibility that Chlamydia in the synovium may produce features of rheumatoid arthritis is discussed.
一名患有3年“类风湿性关节炎”的48岁男性，在18个月内的6次检测中有5次发现其滑膜液淋巴细胞在体外受到衣原体抗原的最大刺激。随后，采用过氧化物酶-抗过氧化物酶技术对滑膜切除术标本进行免疫细胞化学染色，结果显示滑膜中有衣原体抗原。本文讨论了滑膜中的衣原体可能产生类风湿性关节炎特征的可能性。
