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不同种族肥胖人群接受Roux-en-Y胃旁路手术和袖状胃切除术后的体重减轻结果:哪种更有效?

Weight Loss Outcomes following Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in an Ethnically Diverse Bariatric Population: Which Is More Effective?

作者信息

Saeed Saqib, Ahmed Leaque, Khan Khuram, Gray Sanjiv, Saeed Kashif, DePaz Hector, Persaud Amrita, Passos-Fox Bianca, Zhang Kevin C J, Alothman Sara, Suman Paritosh

机构信息

Department of Surgery, Montefiore Medical Center, Bronx, NY, USA.

Department of Surgery, Harlem Hospital Center, New York, NY, USA.

出版信息

Minim Invasive Surg. 2021 Apr 16;2021:9702976. doi: 10.1155/2021/9702976. eCollection 2021.

Abstract

BACKGROUND

Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) have comparable weight loss outcomes in a general bariatric population.

OBJECTIVES

This study aimed to investigate whether similar outcomes can be observed in Hispanic and African American population. . Community Hospital in New York, New York, United States.

METHODS

The 5-year prospective data of patients who underwent LRYGB and LSG at a single center were retrospectively reviewed. The long-term weight loss outcomes between patients who had LRYGB and LSG were compared after adjusting for age, sex, race, diabetes mellitus, and hypertension with the linear mixed-effects or logistic regression model.

RESULTS

Most patients were Hispanic (59.2%) and African American (22.7%). The mean% total weight loss (%TWL) values of patients with BMI <45 kg/m who underwent LRYGB and LSG were 73% and 62% after 1 year, 69% and 56% after 2 years, and 71% and 54% after 5 years, respectively. In patients with a BMI of 45-50 kg/m who underwent LRYGB and LSG, the mean %TWL values were 69% and 56% after 1 year, 75% and 58% after 2 years, and 57% and 45% after 5 years, respectively. Meanwhile, the %TWL values of patients with BMI >50 kg/m who had LRYGB and LSG were 53% and 42% after 1 year, 53% and 45% after 2 years, and 49% and 36% after 5 years, respectively. All results were statistically significant ( < 0.0001) and remained valid after adjusting for cofactors.

CONCLUSION

Thus, LRYGB had consistent and sustained long-term weight loss outcomes compared with LSG in a predominantly ethnically diverse patient population with different BMI. Our study had several limitations in that it is retrospective in nature and some patients were lost to follow-up during the study period.

摘要

背景

在普通肥胖人群中,腹腔镜Roux-en-Y胃旁路术(LRYGB)和腹腔镜袖状胃切除术(LSG)的减重效果相当。

目的

本研究旨在调查在西班牙裔和非裔美国人中是否能观察到相似的结果。美国纽约的社区医院。

方法

回顾性分析在单一中心接受LRYGB和LSG手术患者的5年前瞻性数据。采用线性混合效应或逻辑回归模型,在调整年龄、性别、种族、糖尿病和高血压因素后,比较接受LRYGB和LSG手术患者的长期减重效果。

结果

大多数患者为西班牙裔(59.2%)和非裔美国人(22.7%)。BMI<45kg/m²接受LRYGB和LSG手术的患者,1年后的平均总体重减轻百分比(%TWL)分别为73%和62%,2年后分别为69%和56%,5年后分别为71%和54%。BMI为45-50kg/m²接受LRYGB和LSG手术的患者,1年后的平均%TWL分别为69%和56%,2年后分别为75%和58%,5年后分别为57%和45%。同时,BMI>50kg/m²接受LRYGB和LSG手术的患者,1年后的%TWL分别为53%和42%,2年后分别为53%和45%,5年后分别为49%和36%。所有结果均具有统计学意义(P<0.0001),在调整协变量后仍然有效。

结论

因此,在不同BMI的主要种族多样化患者群体中,与LSG相比,LRYGB具有持续稳定的长期减重效果。我们的研究有几个局限性,即其本质上是回顾性的,并且在研究期间一些患者失访。

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