Ormerod A D, Kobza-Black A, Milford-Ward A, Greaves M W
St. John's Hospital for Diseases of the Skin, London, U.K.
Br J Dermatol. 1988 May;118(5):621-7. doi: 10.1111/j.1365-2133.1988.tb02562.x.
Thirteen patients with both cold and cholinergic urticaria are reported. There was considerable variability, particularly in the cold urticaria which was of the common cold contact type in seven patients, of the generalized cold induced cholinergic type in two and in four patients the lesions induced by direct contact with ice were morphologically like cholinergic urticaria, but appeared despite prior application of an acetyl choline antagonist. The natural history, laboratory findings and the effects of therapy are discussed.
报告了13例同时患有寒冷性和胆碱能性荨麻疹的患者。存在相当大的变异性,尤其是在寒冷性荨麻疹方面,7例患者为常见的冷接触型,2例为全身性冷诱导胆碱能型,4例患者直接接触冰块诱发的皮损在形态上类似胆碱能性荨麻疹,但在预先应用乙酰胆碱拮抗剂的情况下仍会出现。文中讨论了其自然病史、实验室检查结果及治疗效果。