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使用动态下颌前移系统MATRx plus®睡眠的阻塞性睡眠呼吸暂停患者鼾声相关声音的声学和感知特征。

The acoustical and perceptual features of snore-related sounds in patients with obstructive sleep apnea sleeping with the dynamic mandibular advancement system MATRx plus®.

作者信息

Jacquet Wolfgang, De Meyer Micheline M D, Remmers John E, Jahromi Seyed Abdolali Zareian, Hambrook Dillon A, Marks Luc A M

机构信息

Department of Surgical Clinical Sciences CHIR-ORHE, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.

Department of Educational Sciences EDWE-LOCI, Faculty of Psychology and Educational Sciences, Vrije Universiteit Brussel, Brussels, Belgium.

出版信息

Sleep Breath. 2022 Mar;26(1):215-224. doi: 10.1007/s11325-021-02392-2. Epub 2021 May 6.

Abstract

PURPOSE

The effect of snoring on the bed partner can be studied through the evaluation of in situ sound records by the bed partner or unspecialized raters as a proxy of real-life snoring perception. The aim was to characterize perceptual snore events through acoustical features in patients with obstructive sleep apnea (OSA) with an advanced mandibular position.

METHODS

Thirty-minute sound samples of 29 patients with OSA were retrieved from overnight, in-home recordings of a study to validate the MATRx plus® dynamic mandibular advancement system. Three unspecialized raters identified sound events and classified them as noise, snore, or breathing. The raters provided ratings for classification certainty and annoyance. Data were analyzed with respect to respiratory phases, and annoyance.

RESULTS

When subdividing perceptual events based on respiratory phase, the logarithm-transformed Mean Power, Spectral Centroid, and Snore Factor differed significantly between event types, although not substantially for the spectral centroid. The variability within event type was high and distributions suggested the presence of subpopulations. The general linear model (GLM) showed a significant patient effect. Inspiration segments occurred in 65% of snore events, expiration segments in 54%. The annoyance correlated with the logarithm of mean power (r = 0.48) and the Snore Factor (0.46).

CONCLUSION

Perceptual sound events identified by non-experts contain a non-negligible mixture of expiration and inspiration phases making the characterization through acoustical features complex. The present study reveals that subpopulations may exist, and patient-specific features need to be introduced.

摘要

目的

打鼾对同床伴侣的影响可通过同床伴侣或非专业评估者对现场声音记录的评估来研究,以此作为现实生活中打鼾感知的替代指标。目的是通过声学特征对下颌前伸明显的阻塞性睡眠呼吸暂停(OSA)患者的感知性打鼾事件进行特征描述。

方法

从一项验证MATRx plus®动态下颌前伸系统的研究的家庭夜间录音中获取29例OSA患者30分钟的声音样本。三名非专业评估者识别声音事件并将其分类为噪音、打鼾或呼吸声。评估者对分类确定性和烦恼程度进行评分。对数据进行呼吸阶段和烦恼程度方面的分析。

结果

根据呼吸阶段细分感知事件时,对数转换后的平均功率、谱重心和打鼾因子在事件类型之间存在显著差异,尽管谱重心差异不大。事件类型内的变异性很高,分布表明存在亚群体。一般线性模型(GLM)显示患者效应显著。吸气段出现在65%的打鼾事件中,呼气段出现在54%的打鼾事件中。烦恼程度与平均功率的对数(r = 0.48)和打鼾因子(0.46)相关。

结论

非专家识别的感知声音事件包含不可忽视的呼气和吸气阶段混合,使得通过声学特征进行特征描述变得复杂。本研究表明可能存在亚群体,需要引入患者特异性特征。

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