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打鼾声音分析新特征可用于检测阻塞性睡眠呼吸暂停严重程度。

A New Feature with the Potential to Detect the Severity of Obstructive Sleep Apnoea via Snoring Sound Analysis.

机构信息

Department of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.

Department of Respiratory Physiology and Sleep Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo 113-8510, Japan.

出版信息

Int J Environ Res Public Health. 2020 Apr 24;17(8):2951. doi: 10.3390/ijerph17082951.

Abstract

The severity of obstructive sleep apnoea (OSA) is diagnosed with polysomnography (PSG), during which patients are monitored by over 20 physiological sensors overnight. These sensors often bother patients and may affect patients' sleep and OSA. This study aimed to investigate a method for analyzing patient snore sounds to detect the severity of OSA. Using a microphone placed at the patient's bedside, the snoring and breathing sounds of 22 participants were recorded while they simultaneously underwent PSG. We examined some features from the snoring and breathing sounds and examined the correlation between these features and the snore-specific apnoea-hypopnea index (ssAHI), defined as the number of apnoea and hypopnea events during the hour before a snore episode. Statistical analyses revealed that the ssAHI was positively correlated with the Mel frequency cepstral coefficients (MFCC) and volume information (VI). Based on clustering results, mild snore sound episodes and snore sound episodes from mild OSA patients were mainly classified into cluster 1. The results of clustering severe snore sound episodes and snore sound episodes from severe OSA patients were mainly classified into cluster 2. The features of snoring sounds that we identified have the potential to detect the severity of OSA.

摘要

阻塞性睡眠呼吸暂停(OSA)的严重程度通过多导睡眠图(PSG)进行诊断,在此过程中,患者在一夜之间会被 20 多个生理传感器监测。这些传感器经常会打扰患者,可能会影响患者的睡眠和 OSA。本研究旨在探索一种分析患者鼾声以检测 OSA 严重程度的方法。使用放置在患者床边的麦克风,记录 22 名参与者在同时进行 PSG 时的鼾声和呼吸声。我们检查了鼾声和呼吸声中的一些特征,并检查了这些特征与特定于鼾声的呼吸暂停低通气指数(ssAHI)之间的相关性,ssAHI 定义为每小时鼾声前发生的呼吸暂停和低通气事件的数量。统计分析显示,ssAHI 与梅尔频率倒谱系数(MFCC)和音量信息(VI)呈正相关。基于聚类结果,轻度鼾声和轻度 OSA 患者的鼾声主要分为第 1 类。聚类严重鼾声和严重 OSA 患者的鼾声的结果主要分为第 2 类。我们确定的鼾声特征有可能检测 OSA 的严重程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b486/7215580/cdd2faf5e2dc/ijerph-17-02951-g001.jpg

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