Child and Adolescent Outpatient Clinic, Geha Mental Health Center, Petah Tikva, Israel.
Department of Psychiatry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
J Child Adolesc Psychopharmacol. 2021 May;31(4):310-314. doi: 10.1089/cap.2021.0001. Epub 2021 May 5.
This study aimed to evaluate the relationship between baseline test of variables of attention (TOVA) performance, attention-deficit/hyperactivity disorder (ADHD) symptom severity, mood symptoms, proneness to boredom in children with ADHD, and to assess the responses of the various scales to methylphenidate treatment. Thirty-three children and adolescents with ADHD, aged 7-18 years, were assessed at baseline with TOVA and treated for 3 months thereafter with methylphenidate. The ADHD Rating Scale (ADHD-RS), Short Boredom Proneness Scale (SBPS), Children's Depression Inventory (CDI) scale, and CDI-academic and social subscale (CDI-AS) were administered to all participants at baseline and after 3 months of methylphenidate (MPH) treatment. The baseline TOVA reaction time (RT) and RT variability parameters correlated with baseline SBPS and CDI-AS scores as well as with baseline total CDI scores. Significant improvements were found in ADHD-RS, SBPS, and CDI-AS scores after MPH treatment. The alteration in ADHD-RS correlated with parallel changes in SBPS and CDI-AS scores. Mood and proneness to boredom correlate with poor attention-span in children with ADHD. Improvement in ADHD levels after MPH treatment correlates with a parallel decrease in mood symptoms related to academic achievement and social functioning.
本研究旨在评估注意力测试变量(TOVA)基线表现、注意力缺陷多动障碍(ADHD)症状严重程度、情绪症状、ADHD 患儿对无聊倾向与注意力的关系,并评估各种量表对哌甲酯治疗的反应。 33 名 7-18 岁的 ADHD 儿童和青少年在基线时接受 TOVA 评估,此后接受 3 个月的哌甲酯治疗。所有参与者在基线和哌甲酯(MPH)治疗 3 个月后接受 ADHD 评定量表(ADHD-RS)、短时间无聊倾向量表(SBPS)、儿童抑郁量表(CDI)量表和 CDI-学术和社会分量表(CDI-AS)评估。基线时 TOVA 反应时间(RT)和 RT 可变性参数与基线时 SBPS 和 CDI-AS 评分以及基线时总 CDI 评分相关。MPH 治疗后,ADHD-RS、SBPS 和 CDI-AS 评分均显著改善。ADHD-RS 的改变与 SBPS 和 CDI-AS 评分的平行变化相关。 情绪和无聊倾向与 ADHD 患儿注意力持续时间差相关。MPH 治疗后 ADHD 水平的改善与与学业和社会功能相关的情绪症状平行下降相关。