Kim Ji Hoon, Lee Chong Kun, Yu Sung Hoon, Min Byung Duk, Chung Chang Eun, Kim Dong Chul
Department of Plastic and Reconstructive Surgery, Bundang Jesaeng Hospital, Seongnam, Korea.
Arch Craniofac Surg. 2021 Apr;22(2):119-121. doi: 10.7181/acfs.2021.00094. Epub 2021 Apr 20.
Ketamine is used widely in emergency departments for a variety of purposes, including procedural sedation for facial laceration in pediatric patients. The major benefits are its rapid onset of effects, relatively short half-life, and lack of respiratory depression. The known side effects of ketamine are hallucinations, dizziness, nausea, and vomiting. Seizure is not a known side effect of ketamine in patients without a seizure history. Here, we present the case of a patient in whom ketamine likely induced a generalized tonic-clonic seizure when used as a single agent in procedural sedation for facial laceration repair. The aim of this article is to report a rare and unexpected side effect of ketamine used at the regular dose for procedural sedation. This novel case should be of interest to not only emergency physicians but also plastic surgeons.
氯胺酮在急诊科被广泛用于多种目的，包括用于小儿面部裂伤的程序性镇静。其主要优点是起效迅速、半衰期相对较短且无呼吸抑制作用。氯胺酮已知的副作用有幻觉、头晕、恶心和呕吐。在没有癫痫病史的患者中，癫痫发作并非氯胺酮已知的副作用。在此，我们报告一例患者，在面部裂伤修复的程序性镇静中单独使用氯胺酮时，氯胺酮可能诱发了全身强直阵挛性发作。本文的目的是报告氯胺酮在常规剂量用于程序性镇静时出现的一种罕见且意外的副作用。这个新病例不仅应引起急诊医生的关注，也应引起整形外科医生的关注。
