Macaulay A C, Montour L T, Adelson N
Kateri Memorial Hospital Centre, Kahnawake, PQ.
CMAJ. 1988 Aug 1;139(3):221-4.
We surveyed adults with diabetes mellitus and adults without diabetes living in the Mohawk community of Kahnawake, PQ, for clinical characteristics related to vascular disease. People with diabetes were selected from a clinical register; nondiabetic subjects were randomly selected from a community register, with matching for age and sex. The response rates among the two groups were 62% and 39% respectively; groups of 82 and 94 people were obtained. Data were collected by chart review, interview and body measurement. The prevalence rate of ischemic heart disease was 48% for the subjects with diabetes and 22% for those without diabetes. The adjusted odds ratio for development of ischemic heart disease in a person with diabetes was 3.56, for development of cerebrovascular disease 4.57 and for development of peripheral vascular disease 5.51. Logistic regression for macrovascular disease showed that age, sex, smoking, hypertension and obesity could not explain the high rates of complications in the subjects with diabetes. The prevalence rates of ischemic heart disease in adults with and without diabetes are the highest reported in a North American Indian population.
我们对居住在魁北克省卡纳维克莫霍克社区的成年糖尿病患者和非糖尿病成年人进行了调查,以了解与血管疾病相关的临床特征。糖尿病患者从临床登记册中选取;非糖尿病受试者从社区登记册中随机选取,并按年龄和性别进行匹配。两组的应答率分别为62%和39%;最终得到了82人和94人的样本组。数据通过病历审查、访谈和身体测量收集。糖尿病受试者缺血性心脏病的患病率为48%,非糖尿病受试者为22%。糖尿病患者发生缺血性心脏病的调整优势比为3.56,发生脑血管疾病的调整优势比为4.57,发生外周血管疾病的调整优势比为5.51。大血管疾病的逻辑回归分析表明,年龄、性别、吸烟、高血压和肥胖并不能解释糖尿病患者并发症的高发生率。患有和未患有糖尿病的成年人中缺血性心脏病的患病率是北美印第安人群体中报道的最高值。