Kaur Lovleen, Mahajan Bharat B, Mahajan Mohita, Dhillon Shaminder Singh
Department of Dermatology, Venereology and Leprosy, Government Medical College, Amritsar, Punjab, India.
Indian Dermatol Online J. 2021 Feb 22;12(2):302-306. doi: 10.4103/idoj.IDOJ_454_20. eCollection 2021 Mar-Apr.
Verrucous epidermal nevi (VEN) are cutaneous hamartomas characterized by keratinocytic hyperplasia. Majority are linear in distribution and tend to follow the Blaschko lines; however, some may have zosteriform (segmental) or systematized distribution involving widespread areas of skin. The systematized ones are further classified into "" when one-half of the body is affected, and "" showing bilateral distribution, both being the uncommon forms. Although it can affect any body part, it rarely involves the head and neck region with seldom involvement of mucosae, scalp, and ear lobes. We saw a 6-year-old child with multiple hyperpigmented verrucous plaques predominantly present over left half of the body, ipsilateral alopecia scalp, and verrucous lesions involving mucosae of palate and tongue, which were present bilaterally. Previously, case reports of oral lesions related to VEN had demonstrated segmental, midline, or unilateral distribution. Hereby, we report this peculiar case of with bilateral oral mucosal involvement, owing to its rarity.
疣状表皮痣（VEN）是一种以角质形成细胞增生为特征的皮肤错构瘤。大多数呈线状分布，倾向于沿Blaschko线分布；然而，有些可能呈带状疱疹样（节段性）或系统性分布，累及广泛的皮肤区域。当身体一半受累时，系统性的VEN进一步分类为“ ”，而表现为双侧分布的则为“ ”，这两种都是不常见的形式。虽然它可累及身体任何部位，但很少累及头颈部区域，很少累及黏膜、头皮和耳垂。我们见到一名6岁儿童，其左侧身体、同侧头皮脱发区有多个色素沉着的疣状斑块，双侧腭部和舌部黏膜有疣状病变。此前，关于VEN相关口腔病变的病例报告显示为节段性、中线或单侧分布。鉴于其罕见性，在此报告这例双侧口腔黏膜受累的特殊病例。
