Samsamshariat Shiva, Vedaei Amirhossein, Jahangiri Sharare, Gavarti Mahdi Badiee, Sami Ramin, Taheri Abolfazl, Dorooshi Gholamali
Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Student Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2021 Jan 27;10:5. doi: 10.4103/abr.abr_95_20. eCollection 2021.
Paraquat has been recognized as a highly toxic agent for pest removal and is used worldwide. In adults, paraquat poisoning for suicidal attempts is much more common than accidental exposure poisoning. Approximately 20% of patients with paraquat poisoning develop pneumomediastonium as a complication with a mortality rate of approximately 100%. A 19-year-old man patient was admitted to the poisoning emergency department of Khorshid hospital, who had ingested paraquat. He had nausea and vomiting and had normal vital signs and examination in admission. Initial treatment for the patient was done. The patient signs got worsened on the 21 day of hospitalization and had severe emphysema of the superficial and deep spaces of the neck, followed by bilateral pneumothorax, and severe pneumomediastinum. Unfortunately, the patient died on the 27 day of hospitalization. Purpose of the current study is to raise awareness of rare paraquat toxicity complications, treatment, and especially its lethal complications, including pneumomomediastonium.
百草枯被公认为是一种用于除害的高毒药剂,在全球范围内使用。在成年人中,因自杀企图导致的百草枯中毒比意外接触中毒更为常见。约20%的百草枯中毒患者会并发纵隔气肿,死亡率约为100%。一名19岁男性患者因摄入百草枯被收治入霍尔希德医院中毒急诊科。他入院时伴有恶心、呕吐,生命体征及检查均正常。对该患者进行了初始治疗。患者在住院第21天病情恶化,出现颈部浅表和深部间隙严重肺气肿,随后出现双侧气胸及严重纵隔气肿。不幸的是,患者于住院第27天死亡。本研究的目的是提高对罕见的百草枯毒性并发症、治疗,尤其是其致命并发症(包括纵隔气肿)的认识。