Rege-Cambrin G, Mecucci C, Kerim S, Scaravaglio P, Boogaerts M, Van den Berghe H
Dipartimento di Scienze biomediche e Oncologia Umana, University of Torino, Italy.
Cancer Genet Cytogenet. 1988 Aug;34(1):33-40. doi: 10.1016/0165-4608(88)90165-3.
An identical translocation, t(11;21)(q24;q11.2), has been observed in three patients with a myelodysplastic syndrome. In all cases, duplication of the 11q+ marker and loss of the normal chromosome 11 were observed either at diagnosis or during the evolution of the disease. This apparently characteristic chromosome abnormality has not been previously described.