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儿童颅咽管瘤的治疗结果。一种内分泌学治疗方法。

Results of the management of craniopharyngioma in children. An endocrinological approach to the treatment.

作者信息

Kang J K, Song J U

机构信息

Department of Neurosurgery, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.

出版信息

Childs Nerv Syst. 1988 Jun;4(3):135-8. doi: 10.1007/BF00270902.

Abstract

The treatment results of 21 (1972-1982) patients with craniopharyngioma are reported who were treated either by surgery alone or by surgery and radiation therapy. The authors reviewed 14 patients (67%) who were less than 18 years of age at the time of surgery. The eradication was thought to be total in 7 children and subtotal in 7. Radiation was given as part of the initial therapy to 5 children after total excision and to 3 after subtotal removal. There were 2 postoperative deaths. All of the children suffered postoperative hormonal deficiencies. The results of this study indicate that total and subtotal removal followed by RT is an acceptable treatment for craniopharyngioma. Endocrine-deficient children, if treated properly, do well in terms of survival.

摘要

报告了21例(1972 - 1982年)颅咽管瘤患者的治疗结果,这些患者接受了单纯手术或手术加放射治疗。作者回顾了14例(67%)手术时年龄小于18岁的患者。7例儿童被认为肿瘤完全切除,7例为次全切除。5例儿童在肿瘤完全切除后、3例在次全切除后接受了放射治疗作为初始治疗的一部分。术后有2例死亡。所有儿童术后均出现激素缺乏。本研究结果表明,肿瘤全切除或次全切除后行放疗是颅咽管瘤可接受的治疗方法。内分泌功能不足的儿童,若治疗得当,生存情况良好。

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