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老年腰椎减压融合术后早期活动的益处:一项前瞻性队列研究。

Benefits of Early Ambulation in Elderly Patients Undergoing Lumbar Decompression and Fusion Surgery: A Prospective Cohort Study.

机构信息

Department of Spine Surgery, Beijing Jishuitan Hospital, Beijing, China.

Department of Epidemiology, Beijing Jishuitan Hospital, Beijing, China.

出版信息

Orthop Surg. 2021 Jun;13(4):1319-1326. doi: 10.1111/os.12953. Epub 2021 May 7.

Abstract

OBJECTIVE

To evaluate the effects of early ambulation on elderly patients' postoperative physical functional outcomes, complications, 90-day readmission rate, and the length of postoperative hospital stay.

METHODS

This is a prospective cohort study conducted between June 2019 and December 2019. The study enrolled 86 elderly patients (39 males) with newly diagnosed lumbar degenerative disease undergoing single-segment decompression and fusion surgerywere enrolled. Of all 86 patients, 39 voluntarily joined the early ambulation group, and 47 joined the regular ambulation group. The early ambulation group included patients ambulated within 4 h postoperatively, whereas the regular ambulation group included patients who were ambulatory at a minimum of 24 h after surgery. Participants' baseline characteristics, surgical information, ambulation ability, degree of pain, functional scores, postoperative complications, 90-day readmission rate, and length of postoperative hospital stay were recorded.

RESULTS

Participants' baseline demographic characteristics were balanced between the early ambulation group and the regular ambulation group. The operative time and blood loss were similar between groups. The time before the first-time ambulation was 4 ± 0.5 h in the early ambulation group and 28 ± 4.5 h in the regular ambulation group. Ambulating distance was significantly longer in the early ambulation group compared with the regular ambulation group on the 1st (63 ± 45 vs 23 ± 60 m), the 2nd (224 ± 100 vs 101 ± 130 m), and the 3rd (280 ± 102.5 vs 190 ± 170 m) ambulation days based on generalized estimating equation analyses. Generalized estimating equation analyses also demonstrated that the ambulating time was longer in the early ambulation group compared with the regular ambulation group on the 1st (10 ± 5 vs 10 ± 5 min), the 2nd (19 ± 7 vs 15 ± 5 min), and the 3rd (22 ± 16.5 vs 27 ± 12 min) ambulation days. Patients in the regular ambulation group experienced a higher degree of pain than the early ambulation group patients, with an odds ratio of 1.627 (P = 0.002). Short-term functional independence was superior in the early ambulation group, with a lower Roland-Morris disability questionnaire score (P = 0.008) and Oswestry disability index (P < 0.001). The incidences of postoperative urinary retention (early ambulation group: 7.7%, regular ambulation group: 25.5%, P = 0.030) and ileus (early ambulation group: 0%, regular ambulation group: 12.8%, P = 0.030) were significantly higher in the regular ambulation group. The prevalence of at least one complication rate was significantly lower in the early ambulation group than in the regular ambulation group (early ambulation group, 23.1%; regular ambulation group, 46.8%, P = 0.022). The duration of indwelling of the drainage catheter was shorter in the early ambulation group (early ambulation group, 68 ± 24 h; regular ambulation group, 78 ± 20 h, P = 0.001), and the length of the postoperative hospital stay was also shorter in the early ambulation group (early ambulation group, 4 ± 0 days; regular ambulation group: 5 ± 2 days, P < 0.001). However, there was no statistical difference in the 90-day readmission rate between groups.

CONCLUSION

Early ambulation improved patients' postoperative functional status, decreased the incidence of complications, and shortened postoperative hospital stay in elderly patients undergoing lumbar decompression and fusion surgery.

摘要

目的

评估早期活动对老年患者术后身体功能结果、并发症、90 天再入院率和术后住院时间的影响。

方法

这是一项前瞻性队列研究,于 2019 年 6 月至 12 月进行。共纳入 86 名新诊断为腰椎退行性疾病并接受单节段减压融合手术的老年患者(男性 39 名)。在所有 86 名患者中,39 名自愿加入早期活动组,47 名加入常规活动组。早期活动组患者术后 4 小时内开始活动,常规活动组患者术后至少 24 小时开始活动。记录参与者的基线特征、手术信息、活动能力、疼痛程度、功能评分、术后并发症、90 天再入院率和术后住院时间。

结果

早期活动组和常规活动组患者的基线人口统计学特征平衡。两组的手术时间和出血量相似。早期活动组首次活动时间为 4 ± 0.5 小时,常规活动组为 28 ± 4.5 小时。根据广义估计方程分析,早期活动组在第 1 天(63 ± 45 米对 23 ± 60 米)、第 2 天(224 ± 100 米对 101 ± 130 米)和第 3 天(280 ± 102.5 米对 190 ± 170 米)的步行距离明显长于常规活动组。广义估计方程分析还表明,早期活动组在第 1 天(10 ± 5 分钟对 10 ± 5 分钟)、第 2 天(19 ± 7 分钟对 15 ± 5 分钟)和第 3 天(22 ± 16.5 分钟对 27 ± 12 分钟)的步行时间也较长。常规活动组患者的疼痛程度高于早期活动组,优势比为 1.627(P = 0.002)。早期活动组患者短期功能独立性更好,罗尔登-莫里斯残疾问卷评分较低(P = 0.008),Oswestry 残疾指数较低(P < 0.001)。术后尿潴留(早期活动组:7.7%,常规活动组:25.5%,P = 0.030)和肠梗阻(早期活动组:0%,常规活动组:12.8%,P = 0.030)的发生率在常规活动组明显更高。早期活动组至少有一个并发症的发生率明显低于常规活动组(早期活动组:23.1%,常规活动组:46.8%,P = 0.022)。早期活动组引流管留置时间较短(早期活动组:68 ± 24 小时;常规活动组:78 ± 20 小时,P = 0.001),术后住院时间也较短(早期活动组:4 ± 0 天;常规活动组:5 ± 2 天,P < 0.001)。然而,两组 90 天再入院率无统计学差异。

结论

早期活动改善了老年腰椎减压融合术后患者的术后功能状态,降低了并发症的发生率,并缩短了术后住院时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d24f/8274205/53bde34570bd/OS-13-1319-g002.jpg

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