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术后第 0 天开始活动与择期腰椎手术后降低发病率和不良事件相关:密歇根脊柱手术改进协作组(MSSIC)的分析。

Ambulation on Postoperative Day #0 Is Associated With Decreased Morbidity and Adverse Events After Elective Lumbar Spine Surgery: Analysis From the Michigan Spine Surgery Improvement Collaborative (MSSIC).

机构信息

Department of Neurosurgery, Henry Ford Hospital, Detroit, Michigan.

Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan.

出版信息

Neurosurgery. 2020 Aug 1;87(2):320-328. doi: 10.1093/neuros/nyz501.

DOI:10.1093/neuros/nyz501
PMID:31832659
Abstract

BACKGROUND

While consistently recommended, the significance of early ambulation after surgery has not been definitively studied.

OBJECTIVE

To identify the relationship between ambulation on the day of surgery (postoperative day (POD)#0) and 90-d adverse events after lumbar surgery.

METHODS

The Michigan Spine Surgery Improvement Collaborative (MSSIC) is a prospective multicenter registry of spine surgery patients. As part of routine postoperative care, patients either ambulated on POD#0 or did not. The 90-d adverse events of length of stay (LOS), urinary retention (UR), urinary tract infection (UTI), ileus, readmission, surgical site infection (SSI), pulmonary embolism/deep vein thrombosis (PE/DVT), and disposition to a rehab facility were measured.

RESULTS

A total of 23 295 lumbar surgery patients were analyzed. POD#0 ambulation was associated with decreased LOS (relative LOS 0.83, P < .001), rehab discharge (odds ratio [OR] 0.52, P < .001), 30-d (OR 0.85, P = .044) and 90-d (OR 0.86, P = .014) readmission, UR (OR 0.73, P = 10), UTI (OR 73, P = .001), and ileus (OR 0.52, P < .001) for all patients. Significant improvements in LOS, rehab discharge, readmission, UR, UTI, and ileus were observed in subset analysis of single-level decompressions (4698 pts), multilevel decompressions (4079 pts), single-level fusions (4846 pts), and multilevel fusions (4413 pts). No change in rate of SSI or DVT/PE was observed for patients who ambulated POD#0.

CONCLUSION

POD#0 ambulation is associated with a significantly decreased risk for several key adverse events after lumbar spine surgery. Decreasing the incidence of these outcomes would be associated with significant cost savings. As ambulation POD#0 is a modifiable factor in any patient's postoperative care following most spine surgery, it should be encouraged and incorporated into spine-related, enhanced-recovery-after-surgery programs.

摘要

背景

尽管一直被推荐,但术后早期活动的意义尚未得到明确研究。

目的

确定术后第 0 天(术后第 1 天,POD#0)活动与腰椎手术后 90 天不良事件之间的关系。

方法

密歇根州脊柱手术改进协作组(MSSIC)是一个前瞻性的脊柱手术患者多中心登记处。作为常规术后护理的一部分,患者要么在 POD#0 活动,要么不活动。测量了 90 天的住院时间(LOS)、尿潴留(UR)、尿路感染(UTI)、肠梗阻、再入院、手术部位感染(SSI)、肺栓塞/深静脉血栓形成(PE/DVT)和康复设施的处置等不良事件。

结果

共分析了 23295 例腰椎手术患者。POD#0 活动与 LOS 缩短(相对 LOS 0.83,P<.001)、康复出院(优势比 [OR] 0.52,P<.001)、30 天(OR 0.85,P=.044)和 90 天(OR 0.86,P=.014)再入院、UR(OR 0.73,P=10)、UTI(OR 73,P=.001)和肠梗阻(OR 0.52,P<.001)相关。在单节段减压(4698 例)、多节段减压(4079 例)、单节段融合(4846 例)和多节段融合(4413 例)的亚组分析中,观察到 LOS、康复出院、再入院、UR、UTI 和肠梗阻的显著改善。对于在 POD#0 活动的患者,SSI 或 DVT/PE 的发生率没有变化。

结论

POD#0 活动与腰椎手术后多个关键不良事件的风险显著降低相关。降低这些结果的发生率将与显著的成本节约相关。由于 POD#0 活动是大多数脊柱手术后患者术后护理中可改变的因素,因此应鼓励并纳入与脊柱相关的术后康复计划中。

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