Manganese inhibits benzoyl peroxide/copper-dependent lipid peroxidation in the microsomal fraction of rabbit dental pulp.

Tsujimoto Y, Nagashima K, Kawashima T, Takeuchi H, Chiba M, Hashimoto A, Miyoshi T, Takase T, Kikuchi Y, Yamazaki M

Department of Endodontics, Nihon University School of Dentistry at Matsudo, Japan.

Cell Biol Int Rep. 1988 Feb;12(2):143-7. doi: 10.1016/0309-1651(88)90128-2.

Abstract

Of all the cations tested only manganese ion inhibited the benzoyl peroxide/Cu2+-dependent formation of thiobarbituric acid (TBA)-reactive substance. 2. Ki of Mn2+ for the formation of TBA-reactive substance was 5.0 microM. 3. The inhibitory manner of manganese was non competitive against copper.

摘要