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[患者自伤性肺损伤(P-SILI):从病理生理学到具有差异化管理的临床评估]

[Patient self-inflicted lung injury (P-SILI) : From pathophysiology to clinical evaluation with differentiated management].

作者信息

Neetz Benjamin, Flohr Thomas, Herth Felix J F, Müller Michael M

机构信息

Thoraxklinik am Universitätsklinikum Heidelberg, Pneumologie und Beatmungsmedizin, Translational Lung Research Center Heidelberg (TLRC), Röntgenstraße 1, 69126, Heidelberg, Deutschland.

Medizinische Klinik und Poliklinik I, Universitätsklinikum Würzburg, Oberdürrbacherstraße 6, Würzburg, 97080, Deutschland.

出版信息

Med Klin Intensivmed Notfmed. 2021 Oct;116(7):614-623. doi: 10.1007/s00063-021-00823-2. Epub 2021 May 7.

Abstract

The establishment of assisted spontaneous breathing is a phase of ventilation therapy that is generally considered to be beneficial and not dangerous. However, recent findings regarding potential damage from vigorous spontaneous breathing effort should be noticed in patients with acute injured lungs. This syndrome is called patient self-inflicted lung injury. Physicians, nurses and respiratory therapists should be aware of this issue. Parameters that can be determined using esophageal pressure measurement or simple maneuvers on the respirator are helpful when deciding to implement and to monitor assisted spontaneous breathing, even in the acute phases of lung damage. In addition to monitoring, there are therapeutic options for dealing with high respiratory drive or increased breathing effort.

摘要

建立自主呼吸辅助是通气治疗的一个阶段,通常被认为是有益且无危险的。然而,对于急性肺损伤患者,应注意近期有关剧烈自主呼吸努力可能造成损害的研究结果。这种综合征被称为患者自伤性肺损伤。医生、护士和呼吸治疗师应意识到这个问题。在决定实施和监测自主呼吸辅助时,即使在肺损伤的急性期,使用食管压力测量或呼吸机上的简单操作来确定的参数也很有帮助。除了监测之外,还有应对高呼吸驱动力或呼吸努力增加的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cdc/8103432/f6fd3d5704d1/63_2021_823_Fig1_HTML.jpg

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