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保乳手术后肿瘤床加量放疗的应用。

Use of a Tumor Bed Boost in the Radiotherapy after Oncoplastic Breast Conserving Surgery.

出版信息

Chirurgia (Bucur). 2021 Mar-Apr;116(2 Suppl):110-119.

Abstract

Use of a radiotherapy (RT) tumor bed boost in addition to whole breast irradiation (WBI) after oncoplastic breast conserving surgery (OBCS) can be very challenging due to the massive tissue displacements. The aim of our study is to present relevant RT data regarding the use of a boost RT in patients who underwent OBCS and received adjuvant RT at Neolife Medical Center Bucharest. 12 patients treated with intensity modulated radiotherapy (IMRT), after OBCS, using conventional or hypofractionated schedules, between 10/2018 and 12/2020 were included in the study. Pre- and postoperative CT images and surgical clips when available were used for tumor bed (TB) localization and definition of the boost volume. One or more risk factors associated with local recurrence (age under 51 years, high grade tumors, associated ductal carcinoma in situ) were present in 10 patients. Boost RT was delivered in 3 patients. TB localization for the boost RT is difficult without an appropriate marking. Surgical clips and communication between the surgeon and the radiation oncologist are essential for treatment success.

摘要

由于组织的大量移位,在肿瘤整形保乳手术后(OBCS)加用放射治疗(RT)肿瘤床加量对于全乳照射(WBI)来说极具挑战性。我们的研究旨在介绍在罗马尼亚 Neolife 医疗中心接受 OBCS 并接受辅助放疗的患者中,使用 RT 肿瘤床加量的相关放疗数据。 12 例患者于 2018 年 10 月至 2020 年 12 月期间接受了 OBCS,分别采用常规或适形分割调强放疗(IMRT),包括在研究中。术前和术后 CT 图像以及有条件时的手术夹均用于肿瘤床(TB)定位和加量体积的定义。 10 例患者存在局部复发的一个或多个相关危险因素(年龄<51 岁、高级别肿瘤、伴导管原位癌)。3 例患者接受了 RT 肿瘤床加量。 如果没有适当的标记,RT 肿瘤床加量的定位是困难的。手术夹和外科医生与放射肿瘤学家之间的沟通对于治疗成功至关重要。

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