强化艰难梭菌感染预防的药学控制政策，即在抗生素治疗的同时添加三联活菌益生菌。
Enhanced Clostridioides difficile Infection Prevention With a Pharmacy-Controlled Policy That Adds a 3-Strain Lactobacillus Probiotic Concomitantly to Antibiotic Therapy.
机构信息
Microbiology and Infectious Diseases, Centre Intégré de Santé et de Services Sociaux de Lanaudière, Terrebonne, Quebec, Canada.
Research and Development, Bio-K Plus International, Laval, Quebec, Canada.
出版信息
Clin Infect Dis. 2021 Oct 20;73(8):1524-1527. doi: 10.1093/cid/ciab414.
Abstract
When 70% of antibiotic users took a 3-strain Lactobacillus probiotic preparation the hospital-wide rate of healthcare-associated Clostridioides difficile infection improved significantly. The incidence of C. difficile infection for those taking the probiotic along with multiple antibiotics or a single high-risk antibiotic was decreased by at least half.
摘要
当 70%的抗生素使用者服用了一种含有 3 种菌株的乳酸杆菌益生菌制剂时，医院范围内的与医疗保健相关的艰难梭菌感染率显著改善。同时使用益生菌和多种抗生素或单一高风险抗生素的患者中，艰难梭菌感染的发生率至少降低了一半。
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