Li Bao Zhong, Zhang Xu Gang, Li Wei Qing, Li Zhi Tian, Guo Hui Qin, Jiang Fu Sheng
Department of Thoracic Surgery,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Apr 28;43(2):211-215. doi: 10.3881/j.issn.1000-503X.12784.
Objective To evaluate the efficacy and risks of autologous blood patch pleurodesis in patients with persistent air leak(PAL)after lung resection. Methods A total of 97 patients with PAL after lung resection in Beijing Shijitan Hospital from October 2014 to October 2019 were retrospectively reviewed,including 53 treated by autologous blood patch pleurodesis and 44 by the conventional way.The therapeutic effect,adverse reactions and complications were analyzed. Results All the patients with PAL were cured with autologous blood patch pleurodesis.Most air leaks(81.1%)ceased within 48 hours after treatment,and the left 18.9% patients got cured after a repeat.The mean tube retention time and the mean in-hospital stay were 8.4 days and 10.0 days in the autologous blood patch pleurodesis group and 13.5 days and 15.3 days in the conventional treatment group.A prolonged drainage time(P=0.00)and in-hospital stay(P=0.00)were observed in the conventional treatment group.No severe complications were observed except two patients developed slight fever and cutaneous emphysema. Conclusion In our experience,the autologous blood patch pleurodesis is an effective way with low risk of adverse reactions in the treatment of PAL.
目的 评估自体血补片胸膜固定术治疗肺切除术后持续漏气（PAL）患者的疗效及风险。方法 回顾性分析2014年10月至2019年10月在北京世纪坛医院行肺切除术后发生PAL的97例患者，其中53例行自体血补片胸膜固定术，44例行传统方法治疗。分析治疗效果、不良反应及并发症。结果 所有PAL患者经自体血补片胸膜固定术均治愈。多数漏气（81.1%）在治疗后48小时内停止，其余18.9%患者经再次治疗后治愈。自体血补片胸膜固定术组平均置管时间和平均住院时间分别为8.4天和10.0天，传统治疗组分别为13.5天和15.3天。传统治疗组引流时间（P=0.00）和住院时间（P=0.00）延长。除2例患者出现低热和皮下气肿外，未观察到严重并发症。结论 根据我们的经验，自体血补片胸膜固定术是治疗PAL的一种有效方法，不良反应风险低。
