Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA; Department of Urology, Boston University School of Medicine, Boston, MA 02118, USA.
Trends Endocrinol Metab. 2021 Aug;32(8):533-536. doi: 10.1016/j.tem.2021.04.006. Epub 2021 Apr 19.
More men died of coronavirus disease 2019 (COVID-19) than women, suggesting estrogens may protect women. However, COVID-19 deaths among men and women were inconsistent among countries throughout the world. Genetics, epigenetics, and inborn errors of immunity may account for the disparity in mortality among men and women with COVID-19 more than sex steroid hormones.
死于 2019 冠状病毒病（COVID-19）的男性多于女性，这表明雌激素可能对女性具有保护作用。然而，在全球范围内，不同国家 COVID-19 导致的男性和女性死亡率并不一致。遗传学、表观遗传学和先天性免疫错误可能比性激素更能解释 COVID-19 导致的男性和女性死亡率的差异。
