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[缺氧和低温对机体单独及联合作用时骨骼肌和肠道血管共轭功能的特征]

[Characteristics of conjugate functions of the vessels of skeletal muscles and intestines during separate and combined action of hypoxia and hypothermia on the body].

作者信息

Nurmatov A A, Kudriashov Iu A, Tkachenko B I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1988 Apr;74(4):517-24.

PMID:3396714
Abstract

In regimen of the constant blood flow perfusion of skeletal muscles and intestine, hypoxia reduced precapillary resistance and increased the capillary filtration coefficient in both organs whereas postcapillary resistance and capillary pressure were reduced in the intestine and increased in the muscle. Hypothermia increased precapillary resistance in the intestine rather than in the muscle whereas the changes of the capillary filtration coefficient were contrary in both organs; postcapillary resistance and capillary pressure had a tendency to increase in the muscle whereas an increase in these parameters was quite evident in the intestine. Combined effect of hypoxia and hypothermia involved a decrease in precapillary resistance and distensibility of venous vessels, an increase in capillary filtration coefficient in both vascular regions, an increase in postcapillary resistance and in capillary pressure in the intestine, and their decrease in the muscle. In hypothermia (about 30 degrees C), the hypoxic stimulus induced insignificant shifts in all the parameters under study in both organs.

摘要

在骨骼肌和肠道的恒定血流灌注方案中,缺氧降低了两个器官的毛细血管前阻力并增加了毛细血管滤过系数,而肠道的毛细血管后阻力和毛细血管压力降低,肌肉中的则增加。低温增加了肠道而非肌肉的毛细血管前阻力,而两个器官中毛细血管滤过系数的变化则相反;肌肉中的毛细血管后阻力和毛细血管压力有增加的趋势,而在肠道中这些参数的增加则很明显。缺氧和低温的联合作用包括毛细血管前阻力和静脉血管扩张性降低、两个血管区域的毛细血管滤过系数增加、肠道中毛细血管后阻力和毛细血管压力增加,而肌肉中的则降低。在低温(约30摄氏度)时,缺氧刺激在两个器官中所研究的所有参数中引起的变化不显著。

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