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[急性低张性缺氧时骨骼肌的阻力血管、交换血管和容量血管]

[Resistance, exchange and capacitance vessels of the skeletal musculature in acute hypoxic hypoxia].

作者信息

Tkachenko B I, Ibragimov Iu I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Oct;71(10):1229-37.

PMID:4065361
Abstract

In cats under conditions of autoperfusion of hemodynamically isolated m. gastrocnemius, acute hypoxia (10% O2 in nitrogen) increased the precapillary and decreased the postcapillary resistance, reduced the capillary hydrostatic pressure and induced shifts of the capillary filtration coefficient (CFC) by 30% on the average. In cross-circulation performed for analysis of the neurogenic component in the vascular responses, analogous changes of the above parameters were revealed, the CFC decreasing, however. In denervated vascular bed of the m. gastrocnemius, the acute hypoxia decreased the precapillary and increased the postcapillary resistance, the hydrostatic pressure and the CFC increasing. In decentralized vessels of skeletal muscle, hypoxia induced prevalence of filtration while absorption of fluid prevailed in perfusion of the preparation with donor's arterial blood and in recipient's hypoxia.

摘要

在对血流动力学隔离的腓肠肌进行自身灌注的猫中,急性缺氧(氮气中含10%氧气)使毛细血管前阻力增加,毛细血管后阻力降低,毛细血管流体静压降低,平均使毛细血管滤过系数(CFC)偏移30%。在为分析血管反应中的神经源性成分而进行的交叉循环中,也发现了上述参数的类似变化,但CFC降低。在去神经支配的腓肠肌血管床中,急性缺氧使毛细血管前阻力降低,毛细血管后阻力增加,流体静压和CFC增加。在骨骼肌的分散血管中,缺氧导致滤过占优势,而在用供体动脉血灌注标本和受体缺氧时,液体吸收占优势。

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