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由CBS 143953生产的内切-1,4-β-木聚糖酶(丹尼斯克木聚糖酶40000 G/L)组成的饲料添加剂在家禽和猪类动物(丹尼斯克动物营养公司)中的安全性和有效性。

Safety and efficacy of the feed additive consisting of endo-1,4-beta-xylanase produced by CBS 143953 (Danisco Xylanase 40000 G/L) for poultry and porcine species (Danisco Animal Nutrition).

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Glandorf Boet, Anguita Montserrat, Galobart Jaume, Holczknecht Orsolya, Manini Paola, Pizzo Fabiola, Tarrés-Call Jordi, Pettenati Elisa

出版信息

EFSA J. 2021 Apr 29;19(4):e06539. doi: 10.2903/j.efsa.2021.6539. eCollection 2021 Apr.

Abstract

Danisco Xylanase 40000 G/L is the trade name of the feed additive under assessment and contains endo-1,4-beta-xylanase produced by a genetically modified strain of . It is authorised for use in chickens for fattening, laying hens, ducks, turkeys for fattening, all minor poultry species, weaned piglets and pigs for fattening. This scientific opinion concerns the request for the renewal of the authorisation of the additive for the species/categories for which there is an authorisation, a reduction of the minimum recommended level in turkeys for fattening and the extension of use to all poultry species (other than ducks) for fattening or reared for laying/breeding and for laying, suckling piglets and minor growing porcine species. The applicant provided evidence that the additive currently in the market complies with the conditions of the authorisation. There is no new evidence that would lead the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) to reconsider previous conclusions that the additive remains safe for the animal species/categories, the consumer and the environment under the authorised conditions of use. This conclusion applies also to the new target species/categories for which a request of use is made. The additive is not irritant to skin but should be considered as a possible eye irritant and, in common with other proteinaceous substances, respiratory sensitiser. There was no need for assessing the efficacy of the additive in the context of the renewal of the authorisation for chickens for fattening, laying hens, ducks, all minor poultry species, weaned piglets and pigs for fattening. The additive has the potential to be efficacious at 625 U/kg complete feed in all poultry species for fattening (including turkeys) or reared for laying/breeding, and for laying and 2,000 U/kg complete feed in suckling piglets and all minor growing porcine species.

摘要

丹尼斯克木聚糖酶40000 G/L是正在评估的饲料添加剂的商品名,它含有由一种转基因菌株产生的内切-1,4-β-木聚糖酶。它被批准用于育肥鸡、产蛋母鸡、鸭、育肥火鸡、所有小型家禽品种、断奶仔猪和育肥猪。本科学意见涉及对该添加剂在已有授权的物种/类别中的授权续期申请、降低育肥火鸡的最低推荐水平以及将其使用范围扩大到所有用于育肥或饲养用于产蛋/繁殖和产蛋的家禽品种(鸭除外)、哺乳仔猪和小型生长猪品种。申请人提供了证据表明市场上现有的添加剂符合授权条件。没有新的证据会导致欧洲食品安全局动物饲料添加剂和产品或物质专家小组(FEEDAP)重新考虑先前的结论,即在授权的使用条件下,该添加剂对动物物种/类别、消费者和环境仍然是安全的。这一结论也适用于提出使用申请的新目标物种/类别。该添加剂对皮肤无刺激性,但应被视为可能对眼睛有刺激性,并且与其他蛋白质类物质一样,是呼吸道致敏原。在对育肥鸡、产蛋母鸡、鸭、所有小型家禽品种、断奶仔猪和育肥猪的授权续期背景下,无需评估该添加剂的功效。该添加剂在育肥的所有家禽品种(包括火鸡)或饲养用于产蛋/繁殖和产蛋的情况下,在全价饲料中添加625 U/kg可能有效,在哺乳仔猪和所有小型生长猪品种中,在全价饲料中添加2000 U/kg可能有效。

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