癫痫患者使用 kratom 后出现的突破性癫痫发作。
Breakthrough Seizure Associated With Kratom Use in Patients With Epilepsy.
作者信息
Burke Devin J, Mahonski Sarah G, Van Cott Anne C
机构信息
Department of Neurology (DJB, ACVC), University of Pittsburgh Medical Center; Department of Emergency Medicine (SGM), Heritage Valley Health System; and Veteran Affairs Pittsburgh Health System (ACVC), PA.
出版信息
Neurol Clin Pract. 2021 Feb;11(1):78-84. doi: 10.1212/CPJ.0000000000000846.
PURPOSE OF REVIEW
Kratom (mitragynine) is a commercially available herbal supplement that is gaining popularity in the United States. Kratom is associated with a variety of neurologic effects. This review will discuss kratom's association with seizure through 3 cases and highlight what neurologists should know about kratom's clinical effects and legal status.
RECENT FINDINGS
Kratom is currently commercially available, unscheduled by the US Drug Enforcement Administration, and a topic of regulatory debate in the United States. Large poison center reviews have suggested that kratom use is associated with seizure. There have been limited case studies to corroborate this finding. We present 3 cases in which seizures were associated with kratom use in patients treated for epilepsy.
SUMMARY
Since 2008, kratom use is rising in prevalence in the United States aided by lack of regulation. Neurologists need to be aware of its association with seizure and other neurologic side effects.
综述目的
kratom（帽柱木碱）是一种市面上可买到的草药补充剂，在美国正越来越受欢迎。kratom与多种神经学效应相关。本综述将通过3个病例讨论kratom与癫痫发作的关联，并强调神经科医生应该了解的kratom的临床效应和法律地位。
最新发现
kratom目前在市面上有售，未被美国药物执法管理局列入管制，且是美国监管辩论的一个话题。大型中毒控制中心综述表明，使用kratom与癫痫发作有关。有一些有限的病例研究来证实这一发现。我们呈现3例在接受癫痫治疗的患者中癫痫发作与使用kratom相关的病例。
总结
自2008年以来，由于缺乏监管，kratom在美国的使用 prevalence呈上升趋势。神经科医生需要意识到它与癫痫发作及其他神经学副作用的关联。
Zotero 插件