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无管电视辅助胸腔镜手术在纵隔肿瘤切除中的应用

Tubeless video-assisted thoracoscopic surgery in mediastinal tumor resection.

作者信息

Cui Weixue, Huang Danxia, Liang Hengrui, Peng Guilin, Liu Mengyang, Li Run, Xu Xin, He Jianxing

机构信息

Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, China.

出版信息

Gland Surg. 2021 Apr;10(4):1387-1396. doi: 10.21037/gs-20-682.

Abstract

BACKGROUND

It has been reported that tubeless video-assisted thoracoscopic surgery (tubeless-VATS) is feasible and safe for thoracic diseases. Herein, we compared the early outcomes of mediastinal lesion resection between the tubeless and traditional VATS.

METHODS

Clinical data of all patients who underwent thoracoscopic mediastinal tumor resection were retrospectively collected. The study involved two groups: tubeless and traditional VATS group. Propensity score matching (PSM) was applied to eliminate the population bias. Intraoperative and postoperative variables were compared among matched cohorts.

RESULTS

In total, 43 patients in the tubeless group and 231 patients in the traditional VATS group were included. After 1:1 PSM, baseline characteristics were comparable. Anesthesia time (177.63 202.53 min; P=0.004) was shorter in tubeless group, while operation time (90.95 . 101.47 min; P=0.109) was similar. Overall, the total postoperative morbidity rate was similar in the two groups (15% . 12.5%; P=0.556). Specially, 4/43 patients in tubeless VATS group need to be re-put chest tubes postoperatively. A significant lower similar level of visual analogue scale score was observed in tubeless VATS group (1.73±0.48 . 3.41±0.87, P<0.001) in postoperative day 1. Meanwhile, the number of patients using postoperative opioid analgesia was also lower in tubeless VATS group (22.88% . 48.38%, P=0.016). Furthermore, hospital duration after surgery (2.58 . 5.47 days; P=0.002) was shorter in tubeless group.

CONCLUSIONS

Compared with traditional VATS, tubeless VATS for mediastinal tumor may shorten the anesthesia time, decrease postoperative pain and fasten postoperative recovery in carefully selected patients.

摘要

背景

据报道,无管电视辅助胸腔镜手术(无管-VATS)治疗胸部疾病是可行且安全的。在此,我们比较了无管VATS与传统VATS纵隔病变切除术的早期结果。

方法

回顾性收集所有接受胸腔镜纵隔肿瘤切除术患者的临床资料。该研究分为两组:无管组和传统VATS组。采用倾向评分匹配(PSM)以消除人群偏差。比较匹配队列中的术中及术后变量。

结果

无管组纳入43例患者,传统VATS组纳入231例患者。经过1:1 PSM后,基线特征具有可比性。无管组的麻醉时间较短(177.63±202.53分钟;P=0.004),而手术时间相似(90.95±101.47分钟;P=0.109)。总体而言,两组的术后总发病率相似(15%对12.5%;P=0.556)。特别地,无管VATS组中有4/43例患者术后需要重新放置胸管。术后第1天,无管VATS组的视觉模拟量表评分显著更低(1.73±0.48对3.41±0.87,P<0.001)。同时,无管VATS组术后使用阿片类镇痛药的患者数量也更少(22.88%对48.38%,P=0.016)。此外,无管组术后住院时间更短(2.58对5.47天;P=0.002)。

结论

与传统VATS相比,对于纵隔肿瘤,在精心挑选的患者中,无管VATS可能缩短麻醉时间、减轻术后疼痛并加快术后恢复。

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