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在 COVID-19 大流行期间,医院生化临床实验室在进行血液和尿液分析前处理和操作过程中产生的气溶胶。

Aerosol Production During Blood and Urine Pre-analytical Processing and Handling in a Hospital Biochemistry Clinical Laboratory During the COVID-19 Pandemic.

机构信息

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Quebec, QC, Canada.

Faculté des Sciences et de Génie, Département de Biochimie, de Microbiologie et de Bio-informatique, Université Laval, Quebec, QC, Canada.

出版信息

Front Public Health. 2021 Apr 21;9:643724. doi: 10.3389/fpubh.2021.643724. eCollection 2021.

Abstract

The SARS-CoV-2 pandemic has created a troublesome issue for employees in biochemistry clinical laboratories due to fears of aerosol generation during sample treatment. This study was designed to assess aerosol production during the pre-analytical procedures for blood and urine samples using a model bacterium. Air sampling and surface swabbing were conducted during four typical procedures. Bacteria were not recovered in any air or surface samples. Other studies have reported low and undetectable SARS-CoV-2 RNA in blood and urine samples, respectively. Therefore, the occupational risk for employees appears to be low in terms of aerosol exposure from processing SARS-CoV-2 patient samples.

摘要

SARS-CoV-2 大流行期间,由于担心在样本处理过程中产生气溶胶,生物化学临床实验室的员工面临着一个麻烦的问题。本研究旨在使用模型细菌评估血液和尿液样本的分析前程序中气溶胶的产生情况。在四个典型程序中进行了空气采样和表面拭子采样。在任何空气或表面样本中均未回收细菌。其他研究分别报告了血液和尿液样本中 SARS-CoV-2 RNA 水平低且无法检测。因此,处理 SARS-CoV-2 患者样本时,员工因气溶胶暴露而面临的职业风险似乎较低。

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本文引用的文献

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COVID-19: A Risk Assessment Perspective.《COVID-19:风险评估视角》
J Chem Health Saf. 2020 May 11;27(3):160-169. doi: 10.1021/acs.chas.0c00035. eCollection 2020 May 26.

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