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Front Public Health. 2021 Apr 21;9:643724. doi: 10.3389/fpubh.2021.643724. eCollection 2021.
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SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus.在新冠肺炎患者血液制品中检测到的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）RNA与传染性病毒无关。
Wellcome Open Res. 2020 Oct 12;5:181. doi: 10.12688/wellcomeopenres.16002.2. eCollection 2020.
3
SARS-CoV-2 can be detected in urine, blood, anal swabs, and oropharyngeal swabs specimens.SARS-CoV-2 可在尿液、血液、肛拭子和咽拭子标本中检测到。
J Med Virol. 2020 Sep;92(9):1676-1680. doi: 10.1002/jmv.25936. Epub 2020 Apr 30.
4
Evaluation of SARS-CoV-2 RNA shedding in clinical specimens and clinical characteristics of 10 patients with COVID-19 in Macau.评估 SARS-CoV-2 在临床标本中的 RNA 释放情况，以及澳门 10 例 COVID-19 患者的临床特征。
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5
Detection of SARS-CoV-2 in Different Types of Clinical Specimens.SARS-CoV-2 在不同类型临床标本中的检测。
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Microbial aerosol generation during laboratory accidents and subsequent risk assessment.实验室事故期间微生物气溶胶的产生及后续风险评估。
J Appl Microbiol. 2006 Apr;100(4):658-63. doi: 10.1111/j.1365-2672.2005.02798.x.

在 COVID-19 大流行期间，医院生化临床实验室在进行血液和尿液分析前处理和操作过程中产生的气溶胶。

Aerosol Production During Blood and Urine Pre-analytical Processing and Handling in a Hospital Biochemistry Clinical Laboratory During the COVID-19 Pandemic.

机构信息

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Quebec, QC, Canada.

Faculté des Sciences et de Génie, Département de Biochimie, de Microbiologie et de Bio-informatique, Université Laval, Quebec, QC, Canada.

出版信息

Front Public Health. 2021 Apr 21;9:643724. doi: 10.3389/fpubh.2021.643724. eCollection 2021.

DOI:10.3389/fpubh.2021.643724
PMID:33968882
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8097034/
Abstract

The SARS-CoV-2 pandemic has created a troublesome issue for employees in biochemistry clinical laboratories due to fears of aerosol generation during sample treatment. This study was designed to assess aerosol production during the pre-analytical procedures for blood and urine samples using a model bacterium. Air sampling and surface swabbing were conducted during four typical procedures. Bacteria were not recovered in any air or surface samples. Other studies have reported low and undetectable SARS-CoV-2 RNA in blood and urine samples, respectively. Therefore, the occupational risk for employees appears to be low in terms of aerosol exposure from processing SARS-CoV-2 patient samples.

摘要

SARS-CoV-2 大流行期间，由于担心在样本处理过程中产生气溶胶，生物化学临床实验室的员工面临着一个麻烦的问题。本研究旨在使用模型细菌评估血液和尿液样本的分析前程序中气溶胶的产生情况。在四个典型程序中进行了空气采样和表面拭子采样。在任何空气或表面样本中均未回收细菌。其他研究分别报告了血液和尿液样本中 SARS-CoV-2 RNA 水平低且无法检测。因此，处理 SARS-CoV-2 患者样本时，员工因气溶胶暴露而面临的职业风险似乎较低。