Zhao Li-Wei, Sun Ji, Wang Yu-Yong, Hua Run-Miao, Tai Sheng-Cheng, Wang Kai, Fan Yi
Department of Urology, School of Medicine, Hangzhou Normal University, Hangzhou 311121, Zhejiang Province, China.
Department of Urology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou 311202, Zhejiang Province, China.
World J Clin Cases. 2021 Apr 26;9(12):2830-2837. doi: 10.12998/wjcc.v9.i12.2830.
A prostatic stromal tumor is deemed to be a rare oncology condition. Based on the retrospective analysis of clinical data and scientific literature review, a case of prostatic stromal tumor was reported in this article to explore the diagnosis, treatment and prognosis of this rare disease.
The present case involved an older male patient who was admitted to our department for a medical consultation of dysuria. Serum prostate-specific antigen was 8.30 ng/mL, Ultrasound and magnetic resonance imaging suggested evident enlargement of the prostate and multiple cystic developments internally. Considering that the patient was an elderly male with a poor health status, transurethral resection of the prostate was performed to improve the symptoms of urinary tract obstruction. Furthermore, based on histopathologic examination and immunohistochemical staining, the patient was pathologically diagnosed with prostatic stromal tumor. The patient did not receive any further adjuvant therapy following surgery leading to a clinical recommendation that the patient should be followed up on a long-term basis. However, during the recent follow-up assessment, the patient demonstrated recurrence of lower urinary tract symptoms and gross hematuria.
Referring to scientific literature review, we believe that the management of these lesions requires a thorough assessment of the patient. Furthermore, the treatment of prostate stromal tumors should be based on the imaging examination and pathological classification. Active surgical treatment is of great significance to the prognosis of patients, and subsequent surveillance after the treatment is warranted.
前列腺间质瘤被认为是一种罕见的肿瘤疾病。基于临床数据的回顾性分析和科学文献综述,本文报告了一例前列腺间质瘤病例,以探讨这种罕见疾病的诊断、治疗及预后。
本病例为一名老年男性患者,因排尿困难入院咨询。血清前列腺特异性抗原为8.30 ng/mL,超声和磁共振成像显示前列腺明显增大,内部有多个囊性病变。考虑到患者为老年男性且健康状况不佳,行前列腺经尿道切除术以改善尿路梗阻症状。此外,基于组织病理学检查和免疫组化染色,患者病理诊断为前列腺间质瘤。患者术后未接受任何进一步的辅助治疗,因此临床建议对患者进行长期随访。然而,在最近的随访评估中,患者出现下尿路症状复发及肉眼血尿。
参考科学文献综述,我们认为对这些病变的处理需要对患者进行全面评估。此外,前列腺间质瘤的治疗应基于影像学检查和病理分类。积极的手术治疗对患者的预后具有重要意义,治疗后需进行后续监测。