Mindner K, Bergmann I, Sturm G, Liedloff H, Hindersin P, Gleiser W, Till U, Vogel G
Institute of Pathological Biochemistry, Medical Academy of Erfurt.
Haematologia (Budap). 1988;21(1):47-55.
Determinations of the total calcium content and aggregability of the platelets as well as tests of coagulation and fibrinolysis were carried out on 93 patients before undergoing total hip replacement. All patients received low dose heparin, solely or combined with dihydroergotamine. Twenty-six patients developed deep vein thrombosis (DVT) detected by the labelled fibrinogen uptake test and confirmed by ascending phlebography. Only a few tests, among them the total calcium content of platelets, showed a statistical difference between the patients who subsequently developed DVT and those who did not. Combination of several tests by a multivariate statistical analysis programme proved to have more predictive value than the analysis of single tests.
对93例拟行全髋关节置换术的患者进行了血小板总钙含量、聚集性以及凝血和纤维蛋白溶解试验。所有患者均接受低剂量肝素治疗,单独使用或与双氢麦角胺联合使用。通过标记纤维蛋白原摄取试验检测并经上行静脉造影证实,26例患者发生了深静脉血栓形成(DVT)。在这些检测中,只有少数几项,其中包括血小板总钙含量,在随后发生DVT的患者和未发生DVT的患者之间显示出统计学差异。通过多变量统计分析程序对多项检测进行综合分析,其预测价值高于单一检测分析。