Nilsen D W, Jeremic M, Weisert O K
Thromb Haemost. 1980 Jul 15;43(3):194-7.
Preoperative levels of fibrinogen, factors V, VII, VIII and antithrombin III were measured in 25 consecutive patients undergoing total hip replacement. Deep vein thrombosis (D.V.T.) was detected by fibrinogen-uptake test in 60% of the patients. The preoperative fibrinogen level was significantly higher (p < 0.05), and serum antithrombin III was markedly lower (p less than or equal to 0.1) in patients with postoperative D.V.T. The quotient of fibrinogen to serum antithrombin III was significantly higher (p < 0.01) in patients with D.V.T. This quotient may serve as an additional parameter to other clinical and laboratory tests in prediction of postoperative D.V.T. following hip surgery.
对连续25例接受全髋关节置换术的患者进行了术前纤维蛋白原、V、VII、VIII因子及抗凝血酶III水平的测定。通过纤维蛋白原摄取试验在60%的患者中检测到深静脉血栓形成（D.V.T.）。术后发生D.V.T.的患者术前纤维蛋白原水平显著升高（p<0.05），血清抗凝血酶III水平显著降低（p≤0.1）。发生D.V.T.的患者纤维蛋白原与血清抗凝血酶III的比值显著升高（p<0.01）。该比值可作为髋关节手术后预测术后D.V.T.的其他临床和实验室检查的一个附加参数。
