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3D 打印在心血管疾病中的应用:现状与未来展望。

3D Printing in Cardiovascular Disease: Current Applications and Future Perspectives.

机构信息

Cardiac Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.

Vascular Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.

出版信息

Surg Technol Int. 2021 May 20;38:314-324. doi: 10.52198/21.STI.38.CV1422.

DOI:10.52198/21.STI.38.CV1422
PMID:33970475
Abstract

Three-dimensional (3D) printing is emerging as an innovative tool for a tailored approach to endovascular or open procedures. The efforts of different specialists and data analysis can be used to fabricate patient-specific implants, which might have significant impact even in life-saving procedures such as aortic dissections or aortic arch aneurysm. 3D printing is gradually changing the traditional pattern of diagnosis and treatment. This innovative approach allows a perfect match between the patient's anatomy and the prosthetic graft, ideally resulting in better hemodynamics and improved long-term patency related to reduced turbulent flow. Future applications of 3D printing in the cardiovascular field combined with tissue engineering will enhance the therapeutic features of bioprinted tissues and scaffolds for regenerative medicine. This review will summarize the clinical significance of 3D printing in cardiovascular disease, exploring current applications, translational outlooks and future perspectives.

摘要

三维(3D)打印技术作为一种创新工具,正在为血管内或开放手术的个体化方法提供新的途径。不同专业人员的努力和数据分析可以用来制造患者特异性植入物,即使在主动脉夹层或主动脉弓动脉瘤等救生程序中,也可能具有重要影响。3D 打印正在逐渐改变传统的诊断和治疗模式。这种创新方法使得患者解剖结构和人工移植物之间实现完美匹配,理想情况下可以改善血液动力学,减少湍流,从而提高长期通畅率。3D 打印在心血管领域与组织工程的未来应用将增强生物打印组织和支架在再生医学中的治疗特性。本文将综述 3D 打印在心血管疾病中的临床意义,探讨其当前的应用、转化前景和未来展望。

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