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J Stud Alcohol Drugs. 2020 Sep;81(5):556-560.
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Barriers and facilitators to a novel low-barrier hydromorphone distribution program in Vancouver, Canada: a qualitative study.加拿大温哥华一项新型低门槛氢可酮分发计划的障碍和促进因素:定性研究。
Drug Alcohol Depend. 2020 Nov 1;216:108202. doi: 10.1016/j.drugalcdep.2020.108202. Epub 2020 Sep 15.
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'Peer' work as precarious: A qualitative study of work conditions and experiences of people who use drugs engaged in harm reduction work.“同辈”工作也不稳定:一项关于参与减少伤害工作的吸毒者工作条件和经历的定性研究。
Int J Drug Policy. 2020 Nov;85:102922. doi: 10.1016/j.drugpo.2020.102922. Epub 2020 Sep 7.
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Decriminalization of Diverted Buprenorphine in Burlington, Vermont and Philadelphia: An Intervention to Reduce Opioid Overdose Deaths.佛蒙特州伯灵顿市和宾夕法尼亚州费城将被挪用的丁丙诺啡合法化:一项减少阿片类药物过量致死的干预措施。
J Law Med Ethics. 2020 Jun;48(2):373-375. doi: 10.1177/1073110520935353.
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Tackling the overdose crisis: The role of safe supply.应对药物过量危机:安全供应的作用。
Int J Drug Policy. 2020 Jun;80:102769. doi: 10.1016/j.drugpo.2020.102769. Epub 2020 May 1.
6
Unintentional drug overdose: Is more frequent use of non-prescribed buprenorphine associated with lower risk of overdose?非故意药物过量:非处方丁丙诺啡使用频率增加是否与更低的过量风险相关?
Int J Drug Policy. 2020 Apr 17;79:102722. doi: 10.1016/j.drugpo.2020.102722.
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How increasing medical access to opioids contributes to the opioid epidemic: Evidence from Medicare Part D.增加阿片类药物的医疗可及性如何导致阿片类药物流行:来自医疗保险处方药部分的证据。
J Health Econ. 2020 May;71:102286. doi: 10.1016/j.jhealeco.2019.102286. Epub 2020 Mar 4.
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HIV and drug related stigma and risk-taking behaviors among people who inject drugs: a systematic review and meta-analysis.HIV 和与毒品相关的污名与注射吸毒者的冒险行为:系统综述和荟萃分析。
J Addict Dis. 2020 Jan-Mar;38(1):71-83. doi: 10.1080/10550887.2020.1718264. Epub 2020 Jan 31.
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Investigating opioid-related fatalities in southern Sweden: contact with care-providing authorities and comparison of substances.调查瑞典南部与阿片类药物相关的死亡事件:与提供护理的机构的联系以及物质的比较。
Harm Reduct J. 2020 Jan 9;17(1):5. doi: 10.1186/s12954-019-0354-y.
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The effectiveness of prescription drug monitoring programs at reducing opioid-related harms and consequences: a systematic review.处方药物监测项目在减少阿片类药物相关危害和后果方面的有效性:系统评价。
BMC Health Serv Res. 2019 Nov 1;19(1):784. doi: 10.1186/s12913-019-4642-8.

“人们需要这些药物,否则他们就会去服用芬太尼并死亡”:一项定性研究,探讨过量用药流行期间处方阿片类药物转移的“问题”。

"People need them or else they're going to take fentanyl and die": A qualitative study examining the 'problem' of prescription opioid diversion during an overdose epidemic.

作者信息

Bardwell Geoff, Small Will, Lavalley Jennifer, McNeil Ryan, Kerr Thomas

机构信息

British Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, BC, V6Z 2A9, Canada; Department of Medicine, University of British Columbia, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.

British Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, BC, V6Z 2A9, Canada; Faculty of Health Sciences, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada; Centre for Applied Research in Mental Health & Addiction, Simon Fraser University, 515 West Hastings Street, Vancouver, BC, V6B 5K3, Canada.

出版信息

Soc Sci Med. 2021 Jun;279:113986. doi: 10.1016/j.socscimed.2021.113986. Epub 2021 May 3.

DOI:10.1016/j.socscimed.2021.113986
PMID:33971445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8559599/
Abstract

The practice of prescription opioid (PO) diversion remains highly controversial and has been characterized as a source of significant drug-related harm by physicians and public health officials. We critically analyze the "problem" of diversion through an examination of the perspectives of people who divert POs during an overdose epidemic to better understand the practice, including benefits and challenges, as well as how diversion is shaped by structural contexts. Qualitative semi-structured interviews were conducted with 21 participants recruited from ongoing cohort studies involving people who use drugs in Vancouver, Canada. Prohibitive prescribing policies made accessing POs difficult, leading some to smuggle drugs out of clinics. Others would buy POs in bulk or do trades to acquire them. Participants risked having their prescriptions terminated, but rationalized this risk as a protective measure that allows them to provide safer drugs to others (e.g., to prevent overdose or treat withdrawal). Poverty also framed diversion, with some participants diverting their POs to generate income to pay for expenses including food and sometimes illicit fentanyl (perceived as a stronger alternative). However, diversion was shaped by other constraints, including criminalization, negative health impacts from not consistently consuming POs, and supplies running out, which led some participants to rely on other illegal means to generate income. This study highlights the intricate means by which POs are acquired and diverted and how environmental contexts frame how participants negotiated risk and rationalized diversion. Our study provides an alternative perspective on the "problem" of diversion and demonstrate a positive effect in providing a safer drug supply to others during an overdose crisis. Given that drug policy, criminalization, and poverty created challenges, our findings demonstrate the need for strategies that engender greater safety, reduce harm, and alleviate the effects of these constraints, including through policies promoting safer drug supplies, decriminalization, and employment.

摘要

处方阿片类药物(PO)的转移使用行为仍极具争议,医生和公共卫生官员将其视为重大药物相关危害的一个源头。我们通过考察在药物过量流行期间转移使用PO的人群的观点,对转移使用这一“问题”进行批判性分析,以更好地理解这种行为,包括其益处和挑战,以及转移使用行为是如何受到结构背景影响的。我们对21名参与者进行了定性半结构化访谈,这些参与者是从加拿大温哥华正在进行的涉及吸毒者的队列研究中招募的。严格的处方政策使获取PO变得困难,导致一些人从诊所偷运药物。其他人则会批量购买PO或进行交易来获取它们。参与者冒着处方被终止的风险,但将这种风险合理化,认为这是一种保护措施,使他们能够向他人提供更安全的药物(例如,预防药物过量或治疗戒断症状)。贫困也促使了转移使用行为,一些参与者转移他们的PO以赚取收入来支付包括食物以及有时非法芬太尼(被视为更强效的替代品)在内的费用。然而,转移使用行为还受到其他限制因素的影响,包括刑事定罪、不持续使用PO对健康产生的负面影响以及药物供应耗尽,这导致一些参与者依赖其他非法手段来赚取收入。本研究突出了获取和转移使用PO的复杂方式,以及环境背景如何影响参与者对风险的权衡和转移使用行为的合理化。我们的研究为转移使用这一“问题”提供了一个不同的视角,并证明了在药物过量危机期间为他人提供更安全的药物供应所产生的积极作用。鉴于药物政策、刑事定罪和贫困带来了挑战,我们的研究结果表明需要制定能够提高安全性、减少危害并减轻这些限制因素影响的策略,包括通过促进更安全药物供应、非刑事化和就业的政策。