Ohm M J, Scott J R, Galask R P
Am J Obstet Gynecol. 1978 Jan 1;130(1):49-54. doi: 10.1016/0002-9378(78)90437-4.
The purpose of this investigation was to determine the endocervical microflora present in 25 renal allograft recipients hwo were receiving therapeutic dosages of azathioprine or cyclophosphamide and prednisone. The aerobic flora was similar to that found in other populations. However, these immunosuppressed patients had more different anaerobic species per culture than were found in most other populations. This was reflected in the more frequent isolation of many species of anaerobic bacteria, especially the anaerobic gram-negative rods. The clinician should be aware of these differences since they may be significant in regard to gynecologic or obstetric postoperative infectious morbidity in women using immunosuppressive medications.
本研究的目的是确定25名接受硫唑嘌呤或环磷酰胺及泼尼松治疗剂量的肾移植受者宫颈内的微生物群。需氧菌群与其他人群中发现的相似。然而，这些免疫抑制患者每次培养中发现的厌氧菌种比大多数其他人群更多。这反映在许多厌氧菌，尤其是厌氧革兰氏阴性杆菌的分离频率更高。临床医生应意识到这些差异，因为它们可能对使用免疫抑制药物的女性的妇科或产科术后感染发病率具有重要意义。
