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[通过输注甘油三酯乳剂抑制肌肉氨基酸释放]

[Inhibition of muscle amino acid release by infusion of a triglyceride emulsion].

作者信息

Rett K, Wicklmayr M, Baldermann H, Schwiegelshohn B, Dietze G, Mehnert H

机构信息

III. Med. Abteilung, Krankenhaus München-Schwabing und Forschergruppe Diabetes.

出版信息

Infusionstherapie. 1988 Apr;15(2):78-82.

PMID:3397192
Abstract

Amino acid balances of 12 healthy volunteers were investigated with the forearm technique under the influence of an intravenous infusion of a long-chain triglyceride emulsion (LCT). Arterial concentrations of the amino acids declined due to a decrease of basal muscular release of most of the amino acids. Decreased phenylalanine and tyrosine output suggest that muscular proteolysis might be inhibited. With constant insulin and substantially unchanged blood glucose concentrations, this is apparently due to the increased concentration of free fatty acids.

摘要

采用前臂技术,在静脉输注长链甘油三酯乳剂(LCT)的影响下,对12名健康志愿者的氨基酸平衡进行了研究。由于大多数氨基酸的基础肌肉释放减少,动脉血中氨基酸浓度下降。苯丙氨酸和酪氨酸输出减少表明肌肉蛋白水解可能受到抑制。在胰岛素水平恒定且血糖浓度基本不变的情况下,这显然是由于游离脂肪酸浓度增加所致。

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