Division of Neonatology, Department of Pediatrics, University of Utah, 295 Chipeta Way, Salt Lake City, UT 84108, USA.
Division of Neonatology, Department of Pediatrics, University of Utah, 295 Chipeta Way, Salt Lake City, UT 84108, USA.
Obstet Gynecol Clin North Am. 2021 Jun;48(2):311-323. doi: 10.1016/j.ogc.2021.02.004.
Fetal growth restriction (FGR) describes a fetus' inability to attain adequate weight gain based on genetic potential and gestational age and is the second most common cause of perinatal morbidity and mortality after prematurity. Infants who have suffered fetal growth restriction are at the greatest risks for short- and long-term complications. This article specifically details the neurologic and cardiometabolic sequalae associated with fetal growth restriction, as well as the purported mechanisms that underlie their pathogenesis. We end with a brief discussion about further work that is needed to gain a more complete understanding of fetal growth restriction.
胎儿生长受限(FGR)描述了胎儿根据遗传潜力和胎龄无法获得足够体重增加的情况,是仅次于早产的围产期发病率和死亡率的第二大常见原因。患有胎儿生长受限的婴儿面临着短期和长期并发症的最大风险。本文专门详细介绍了与胎儿生长受限相关的神经和心脏代谢后遗症,以及潜在的发病机制。最后,我们简要讨论了需要进一步开展工作,以更全面地了解胎儿生长受限。