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食管贲门失弛缓症的外科治疗结果。1856例多中心回顾性研究。欧洲食管疾病研究小组(GEEMO)多中心回顾性研究。

Results of surgical treatment of esophageal achalasia. Multicenter retrospective study of 1,856 cases. GEEMO (Groupe Européen Etude Maladies Oesophagéennes) Multicentric Retrospective Study.

作者信息

Moreno González E, Garcia Alvarez A, Landa Garcia I, Gómez Gutierrez M, Rico Selas P, Garcia Garcia I, Jover Navalón J M, Arias Diaz J

机构信息

Servicio de Cirugía General y Aparato Digestivo C, Hospital Primero de Octubre, Universidad Complutense, Madrid, Spain.

出版信息

Int Surg. 1988 Apr-Jun;73(2):69-77.

PMID:3397260
Abstract

A retrospective analysis of 1,856 patients treated by esophageal achalasia in 23 different surgical departments from seven countries is reported. The predominant symptom was dysphagia (100%), pain, vomiting and weight loss (76.1%). The most useful diagnostic methods were: barium meal (85%), manometry (100%), endoscopy (100%) and 99mTc (100%). Conservative treatment (5.45%) was useful in 5.8% only. Dilatation (16.9%) produced amelioration in 65.9%. Thoracotomy was used in 20.9% and middle line laparotomy in 79.2%. Heller esophagomyotomy was performed in 99.52% associated with anterior fundoplasty in 79.8% and postero-lateral (Mark IV) in 9.75%. Most of the patients were controlled through barium meal, esophagoscopy, esophageal manometry, pHmetry and 99mTc ingestion. Good results after Heller's myotomy with anterior fundoplication were 81.7% and poor 7.2%. Recurrence of achalasia was present in 184 patients. A new esophagomyotomy was performed on 58.6% and distal esophageal resection in 62 (35.3%). In total, 988 patients were reviewed once a year. Absence of gastroesophageal reflux was shown in 73.9% of the explored patients.

摘要

报告了对来自七个国家23个不同外科科室治疗的1856例食管失弛缓症患者的回顾性分析。主要症状为吞咽困难(100%)、疼痛、呕吐和体重减轻(76.1%)。最有用的诊断方法为:钡餐(85%)、测压(100%)、内镜检查(100%)和99mTc(100%)。保守治疗(5.45%)仅对5.8%的患者有效。扩张术(16.9%)使65.9%的患者病情改善。开胸手术占20.9%,中线剖腹手术占79.2%。99.52%的患者进行了Heller食管肌层切开术,79.8%联合前胃底折叠术,9.75%联合后外侧(Mark IV)胃底折叠术。大多数患者通过钡餐、食管镜检查、食管测压、pH测定和99mTc摄取进行评估。Heller肌层切开术联合前胃底折叠术的良好效果为81.7%,差的为7.2%。184例患者出现失弛缓症复发。58.6%的患者再次进行了食管肌层切开术,62例(35.3%)进行了食管远端切除术。总共对988例患者进行了每年一次的复查。73.9%的受检患者未出现胃食管反流。

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